University of Hyderabad (UoH) 2011 M.Sc BioTechnology Entrance for (Animal ) - Question Paper
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Department of Animal Sciences ENTRANCE EXAMINATION, JUNE 2011 M. Sc Animal Biotechnology Time: 2 hours Maximum Marks: 100 INSTRUCTIONS: PLEASE READ BEFORE ANSWERING!
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1. The complete aerobic respiration of glucose produces | |||||||||||||||||||||||||||||||||||||||
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5. Which of the following techniques are used for the analysis of restriction fragment length polymorphisms?
A) Electrophoresis & chromatography B) Restriction enzyme digestion &
electrophoresis
C) Methylation & Restriction enzyme D) Restriction enzyme digestion & digestion chromatography
6. Lipid A stimulates the synthesis of which factor?
A) Transforming growth factor (TGF) B) Tumor necrosis factor (TNF)
C) Epidermal growth factor (EGF) D) Platelet derived growth factor (PDGF)
7. The only living echinoderms which are fully sessile
A) Sea urchins B) Sea cucumbers
C) Sand dollars D) Sea lilies
8. Which one of the following agent is commonly used for determining the N-terminal amino acid of a polypeptide?
A) Trypsin B)
Phenyl isothiocyanate Aminopeptidase
Independent of pH
Dependent on the enzyme concentration
C) Cyanogen bromide D)
9. The Michaelis-Menten constant Km is
A) Numerically equal to Vi Vmax B)
C) Numerically equal to substrate D) concentration that gives half-maximal velocity
10. The unfertilized eggs laid by queen bee develop into
A) Queens B) Workers
C) Hermaphrodite D) Drones
11. The chromosome composition seen in different syndromes is given below. Identify the pair that is mismatched.
A) Turner's syndrome - 45 (AA+XO) B) Patau's syndrome - 45: Monosomy
of 13th chromosome
C) Kleinfelter's syndrome - 47 D) Down's syndrome - 47: Trisomy of
(AA+XXY) 21st chromosome
12. Which one of the following sequences shows the correct hierarchy of classification, going from the most inclusive to the least inclusive?
Kingdom, order, phylum, class, family, genus, species Kingdom, class, order, family, genus, species
A) Kingdom, phylum, order, class, B) family, genus, species C) Kingdom, phylum, class, order, D) family, genus, species
13. Silicon is a
A) Insulator B)
Conductor
Non-conductor
C) Semiconductor D)
V -1ST
14. Which of the following disease is not caused by bacteria?
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A) Plague B) Yellow fever
C) Cholera D) Tuberculosis
15. If an affected male has all affected daughters, but no affected sons, the trait is likely to be an
A) X-linked recessive trait B) Autosomal recessive trait
C) Autosomal dominant trait D) X-linked dominant trait
16. The molarity of a solution containing 5.844 gram NaCI in 100 mL is
A) 0.01 M B) I M
C) 0.1 M D) 10 M
17. The phylum of plants that includes mosses is
A) Anthocerophyta B) Lycophyta
C) Bryophyta D) Pterophyta
18. The premature aging syndrome caused due to the mutation in DNA repair enzymes is
A) Schizophrenia B) Dementia
C) Aphasia D) Hutchinson-Gilford Progeria
19. Which one of the following pairs are analogous structures?
A) The front leg of horse and a B) The front leg of frog and a bat wing human arm
C) The wings of bird and butterfly D) The front flipper of a whale and a wings human arm
20. Hydrolysis of one ATP molecule to ADP releases_calories of energy.
A) 730 B) 7,300
C) 68,600 D) 73,000
21. Which one of the following DNA duplex has highest melting temperature?
A) 5'ATGGCTCGT 3' B) 5' GGCTGGAGA 3'
3' TACCGAGCA 5' 3' CCGACCTCT 5'
C) 5' ATGATACTG 3' D) 5' ATGGGCCCTG 3'
3' TACTATGAC 5' 3' TACCCGGGAC 5'
22. Receptors for which of the following hormones are found in the cytoplasm of responsive cells?
A) Thyroid hormone and insulin B) Thyroid hormone and estrogen
C) Insulin and estrogen D) Glucagon and estrogen
23. The cooking time for food is reduced in a pressure cooker because
A) Heat is more evenly distributed in B) Bolling point of the water involved in the cooking space cooking is decreased
C) The higher pressure inside the D) Boiling point of the water involved in cooker pulverizes the food material cooking is increased
24. The animals that are genetically constructed to differ at one particular locus are called as
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A) Congenic B) Chimeric
C) Hybrid D) Transgenic
25. Sequencing and analysis of rRNA has divided the living world into three domains called
A) Fungi, plants and animals B) Archaea, eukarya & virus
C) Bacteria, archaea & eukarya D) Bacteria, archaea & plants
26. A process in which movement of a molecule across the membrane down its concentration gradient is coupled to the movement of a second molecule up Its concentration gradient and across the membrane in opposite direction is called -
A) Active transport B) Antiport
C) Uniport D) Symport
27. The matrix of mitochondria contains
A) Citric acid cycle intermediates B) FADH2
C) A high concentration of glucose D) Glycogen
28. Planarian use_for excretion
A) Nephridia B) Flame cells
C) Uriniferous tubules D) Malpighian tubules
29. The occurrence of tetratype in the acetomycete fungi is possible only If the crossing over occurred during the
A) G1 phase B) Four-strand stage
C) Two-strand stage D) S phase
30. In mammals, the diaphragm separates the
A) Thoracic cavity from the pericardial 3) Peritoneal cavity from pericardial cavity cavity
C) Peritoneal cavity from the thoracic D) Thoracic cavity from the pelvic cavity cavity
31. Which one of the following metabolites is not directly produced in the hexose monophosphate shunt pathway?
A) Fructose-6-phosphate B) Gluconolactone-6-phosphate
C) Erythrose-4-phosphate D) Dihydroxyacetone phosphate
32. Cytochromes are found in
A) Cristae of mitochondria B) Inner mitochondrial membrane
C) Matrix of mitochondria D) Outer mitochondrial membrane
33. Tapeworms attach to the digestive lining of the host by means of their
A) Proglottid B) Stylete
C) Scolex D) Mastax
34. If the paternal chromosomes have alleles A, Bf c and the maternal chromosomes have a, b, C - then the chromosomes that are not a product of crossing over are -
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A) ABC and a b c B) A b C and a B c
C) Abe and a B C D) A Be and a b C
35. Nondisjunction involving the X chromosomes may occur during oogenesis and produce two kinds of eggs. If normal sperms fertilize these two types, which of the following pairs of genotypes are possible?
A) XX and XY B) XXY and XO
C) XX and XO D) XXY and YO
36. Methionyl-transfer RNA is used for initiation of protein synthesis by which of the following?
A) Chloroplast B) Eukaryotic mitochondrial ribosomes
C) Bacterial ribosomes D) Eukaryotic cytoplasmic ribosomes
37. Which component in the viral envelope attaches the human deficiency virus (HIV) to host cells?
A) gpl20 B) pl8
C) gp41 D) p24
38. Which one of the following could be used to distinguish between an aldose and a ketose?
A) Fehling's reagent B) Tolien's reagent
C) Br2 water D) Feulgen's reagent
39. Common method used for determination of the three dimensional structure of proteins is
A) Edman degradation B) Two dimensional gel electrophoresis
C) MALDI TOF analysis D) X-ray crystallography
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40. Which one of the following is correct? A) Animal cells produce cellulase B) which hydrolyzes cellulose C) Carbohydrates are absorbed D) primarily in the form of disaccharides |
Glycogen hydrolysis is promoted by the hormone glucagon Insulin has little effect on carbohydrate metabolism |
41. If a phosphodiester bond in one strand of double stranded circular DNA is broken, the DNA is said to be
A) Digested B) Nicked
C) Cleaved D) Linearized
42. The first virus to be purified was
Smallpox
Tobacco Mosaic virus
A) Influenza virus B)
C) Polio virus D)
43. The amino acid leucine has the following side chain.
A) (CH3)2 - CH - CH2 - B) CH3 - CH (CH)2 -
C) CH3 - CH (OH) D) CH3 - CH2 - CH (CH3)-
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44. Which one of the following is WOT a part of the immune system?
A) Spleen B) Thymus
C) Pancreas D) Tonsil
45. Liebermann's reaction is used for detection of
A) aniline B) benzoic acid
C) phenol D) nitrobenzene
46. When an animal cell is placed In 0.5 M sucrose solution, its volume does not alter. When the same cell is transferred to a 0.5 M NaCI solution, the volume of the cell will -
A) Remain unchanged B) Increase
C) Decrease D) Increase and then decrease
47. Which one of the following is mismatched!
A) Matrix - extracellular material in B) Ligaments - bind muscles to bone connective tissue
C) Adipose cells * found in loose D) Cardiac muscle cells - multiple nuclei connective tissue
48. The nucleic add which is highly modified by extensive methylation after synthesis is
A) hnRNA B) mRNA
C) rRNA D) tRNA
49. Which one of the following is an acidic amino acid?
A) Lysine B) Isoleucine
C) Aspartic acid D) Proline
50. Genetic recombination in bacteria occurs through the transfer of
A) Pili B) Gametes
C) Endospores D) Plasmids
51. The second messenger which plays a crucial role in regulating the synthesis and breakdown of glycogen In liver and muscle cells is
A) IP3 B) cGMP
C) DAG D) cAMP
52. What blocks myosin from binding to actin, when the muscle is at rest?
A) Acetylcholine B) ATP
C) Tropomyosin D) Troponin
53. Which one of the following is not a cancer drug?
A) Daunorubicin B) Cisplatin
C) Methotrexate D) Isoniazid
54. Isotypes defer to variation in the
A) Light chain variable region B) Heavy chain constant region
C) Light chain constant region D) Heavy chain variable region
55. When chromosome breakage occurs and the broken segment rotates by 180 degrees before reunion, the resulting chromosome aberration is known as
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A) Insertion B) Translocation
C) Frame shift D) Inversion
56. A common method for separating cell organelles and insoluble material from soluble proteins -
A) Filtration B) Differential centrifugation
C) Polyacrylamide gel electrophoresis D) Column chromatography
57. Cystic fibrosis is caused by _mutation.
A) Autosomal dominant B) Autosomal recessive
C) Sex-linked recessive D) Sex-linked dominant
58. In sensory neurons, stimuli are conducted through
A) Axons B) Cell body
C) Dendrites D) Myelin sheath
59. According to molecular definition of a gene, which one of the following is not a part of eukaryotic gene?
A) Promoter B) Poly (A) tail
C) Enhancer D) Polyadenylation signal
60. At room temperature formaldehyde changes into
A) Acetic acid B) Paraldehyde
C) Acetaldehyde D) Trioxane
61. Which one of the following is part of the gynoecium?
A) Carpel B) Filament
C) Stamen D) Sepal
62. The major class of insoluble fibrous protein present in the extracellular matrix and in connective tissue is
A) Collagen B) Cadherin
C) Actin D) Flbronectin
63. The following method helps in determining the genotype of an individual for a particular trait
A) Back cross B) Test cross
C) Monohybrid cross D) Dihybrid cross
64. The rhythmic beating of the heart is initiated by the-
A) Purkinje fibers B) Sinoatrial node
C) Atrioventricular node D) Bundle of His
65. Which one of the following is an innate immune cell type?
ft ) B lymphocyte ) T lymphocyte
C ) NKT cells D ) Macrophage
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66. Which one of the following is not characteristic of members of the plant kingdom?
A) Chlorophyll a B) Chlorophyll b
C) Carotenoids D) Chlorophyll c
67. Releasing hormones (TRH, GnRH etc.) in higher animals are synthesized and secreted by
A) Adenohypophysis B) Hypothalamus
C) Neurohypophysis D) Pars-intermedia
68. The neurotransmitter at the neuromuscular junction is-
A) Acetyl choline B) Serotonin
C) Dopamine D) Epinephrine
69. Which one of the following is not a primary alcohol?
A) Isopropyl alcohol B) Ethanol
C) Benzyl alcohol D) Methanol
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70. Green algae, recently been investigated as food source in several nations is
A) Volvox B) Pseudomonas
C) Chlamydomonas D) Chlorella
71. The virus commonly used for the management of insect pests as well as a vector for production of recombinant proteins is
A) Baculovirus B) Adenovirus
C) Parvovirus D) Retrovirus
72. Two antagonistic hormones are-
A) MSH & TSH B) Oxytocin & Prolactin
C) ADH & GH D) Calcitonin & Parathormone
73. Which has the maximum percentage of Cl?
A) BHC B) PVC
C) Neoprene D) DDT
74. The inflammatory response includes all of the following except
A) Phagocytic attack B) Temperature increase
C) Increased blood flow D) Vessel constriction
75. Worlds natural gas reservoirs are primarily produced by
A) Archaebacteria B) Actinomyces
C) Primitive protists D) Anaerobic fungi
76. Components of animal cell cytoskeleton found in cilia and flagella that direct chromosomal movement during cell division are
A) Microfilaments B) Microtubules
C) Intermediary filaments D) Microtubules and microfilaments
77. Solid C02 is an example of
A) Ionic crystal
B)
D)
Molecular crystal Metallic crystal
Mannose and fructose Sucrose and fructose
C) Covalent crystal
78. The following are epimers of glucose
A) Galactose and fructose B)
C) Mannose and galactose D)
79. Enzymes from the following organelle are involved in the oxidation of fatty acids, but the released energy is not used for ATP synthesis
A) Peroxisomes B) Lysosomes
C) Mitochondria D) Ribosomes
80. While most of the insects have four wings, the following have only two
A) Cockroach B) Honeybee
C) Butterfly D) Housefly
81. Enzyme produced in the kidney, which catalyzes the cleavage of angiotensinogen present in the blood-
A) Angiotensin B) Bradykinin
C) Renin D) Kynurenlne
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82. Cerebellum regulates A) Body temperature C) Sleep-wake cycle |
B) Learning and memory D) Movement and balance |
83. If radioactive sulphur is added to culture medium of E. coli, the radioactive label after 48 hours will be localized in
B) RNA
A) DNA C) Enzymes
D) Phospholipid
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84. Vertebrate lungs are derived from . A ) Ectoderm C ) Epiderm 85. Giucokinase A) Is widely distributed in most of the mammalian tissues C) Has high Km for glucose |
Endoderm Mesoderm ) B) Is inhibited by glucose-6-phosphate D) Catalyzes a reversible reaction |
86. Humans can digest starch and not cellulose. Both of them contain monomeric glucose units. Starch is digested due to specificity of the intestinal enzymes for
A) a l->4 linkage B) 0 l->4 linkage
C) a l->6 linkage D) (3 l->6 linkage
87. Drugs that prevent the formation of bacterial cell wall are
A) quinolones B) aminoglycosides
C) tetracycline D) beta-lactams
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88. Heat shock proteins, originally identified as proteins expressed in response to stress, also function as
A) Protein kinase B) GTPase activating proteins
C) Molecular chaperones, which assist D) Proteases degrading ubiquitin-tagged in de novo protein folding proteins
89. When a lead storage battery is discharged
A) S02 is evolved B) Sulphuric acid is consumed
C) Lead is formed D) Lead sulfate is consumed
90. The genome of an organism contains 20% adenine residue. Which one of the following statement is correct?
A) G + C content is 20% B) G + C content is 40%
C) G + C content is 60% D) G + C content is 80%
91. If one mL of 0.01 M HCI is diluted to 100 mL at 25 C, what will be the pH of the resulting solution?
A) 7 B) 5
C) 4 D) 2
92. Which one of the following pathway is very active in the tissues involved in lipogenesis and nucleic acid biosynthesis?
A) Glycolysis B) HMP shunt pathway
C) P oxidation D) TCA cycle
93. Which one of the following is a human cell line?
A) CHO B) BHK-21
C) Hela D) Sf-9
94. When a gasoline is given "octane number" 80, it means it contains
A) 80% iso-octane B) 80% octane
C) 20% iso*octane D) 20% benzene
95. The bacteria which utilize C02 as the sole carbon source and obtain energy by oxidation and reduction of inorganic substances are called as
A) Chemolithotrophs B) Chemoheterotrophs
C) Photoautotrophs D) Photoheterotrophs
96. Human albinism is caused by recessive gene 'a'. A child has albinism, although none of the parents are affected. What is the genotype of parents?
A) AA and AA B) Aa and AA
C) Aa and aa D) Aa and Aa
97. Viral replication within cells is inhibited by
A) IL-1 B) IFN-y
C) IL- 4 D) TNF- 0
98. In the mitochondrial genome, the stop codon is
A) UAA B) UGA
C) UUU D) AGA
fl/CrOkltf CoJLt B
99. Which one of the following is a polyatomic cation?
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A) Mg?+ B) OH'
C) Cu2+ D) NH4*
100. Human embryonic stem cells are commonly derived from
A) Inner cell mass (ICM) B) Trophoblast
C) Complete blastocyst D) Cord blood cells
For rough work
V-liT 11
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Attachment: |
| Earning: Approval pending. |
