University of Hyderabad (UoH) 2011 M.Sc BioTechnology Entrance for (Animal ) - Question Paper
Department of Animal Sciences ENTRANCE EXAMINATION, JUNE 2011
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M. Sc Animal Biotechnology Time: 2 hours Maximum Marks: 100 INSTRUCTIONS: PLEASE READ BEFORE ANSWERING!
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1. The complete aerobic respiration of glucose produces | ||||||||||||||||||||||||||||||||||||||||||
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5. Which of the following techniques are used for the analysis of restriction fragment length polymorphisms?
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A) Restriction enzyme digestion & B) Electrophoresis & chromatography electrophoresis
C) Methylation & Restriction enzyme D) Restriction enzyme digestion & digestion chromatography
6. Lipid A stimulates the synthesis of which factor?
A) Transforming growth factor (TGF) B) Tumor necrosis factor (TNF)
C) Platelet derived growth factor D) Epidermal growth factor (EGF))
(PDGF
7. The only living echinoderms which are fully sessile
A) Sea urchins B) Sea lilies
C) Sand dollars D) Sea cucumbers
8. Which one of the following agent is commonly used for determining the N-terminal amino acid of a polypeptide?
A) Trypsin B) Aminopeptidase
C) Cyanogen bromide D) Phenyl isothiocyanate
9. The Michaelis-Menten constant Km is A) Numerically equal to 1/j Vmax C) Independent of pH 10. The unfertilized eggs laid by queen A) Drones C) Hermaphrodite |
B) Numerically equal to substrate concentration that gives half-maximal velocity D) Dependent on the enzyme concentration bee develop into B) Workers D) Queens |
11. The chromosome composition seen in different syndromes is given below. Identify the pair that is mismatched.
A) Turner's syndrome - 45 (AA+XO) B) Kleinfelter's syndrome -47 (AA+XXY)
C) Patau's syndrome - 45: Monosomy D) Down's syndrome - 47: Trisomy of
of 13th chromosome 21st chromosome
12. Which one of the following sequences shows the correct hierarchy of classification, going from the most inclusive to the least inclusive?
A) Kingdom, phylum, order, class, B) family, genus, species C) Kingdom, phylum, class, order, D) family, genus, species |
Kingdom, class, order, family, genus, species Kingdom, order, phylum, class, family, genus, species |
13. Silicon is a
A) Insulator
C) Conductor
B) Semiconductor D) Non-conductor
14. Which of the following disease is not caused by bacteria?
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A) Plague B) Tuberculosis
C) Cholera D) Yellow fever
15. If an affected male has all affected daughters, but no affected sons, the trait is likely to be an
A) X-linked recessive trait B) X-linked dominant trait
C) Autosomal dominant trait D) Autosomal recessive trait
16. The molarity of a solution containing 5.844 gram NaCI in 100 mL is
A) 0.01 M B) IM
C) 0.1 M D) 10 M
17. The phylum of plants that includes mosses is
A) Anthocerophyta B) Lycophyta
C) Pterophyta D) Bryophyta
18. The premature aging syndrome caused due to the mutation in DNA repair enzymes is
A) Schizophrenia B) Hutchinson-Gilford Progeria
C) Aphasia D) Dementia
19. Which one of the following pairs are analogous structures?
A) The wings of bird and butterfly B) The front leg of frog and a bat wing wings
C) The front leg of horse and a D) The front flipper of a whale and a human arm human arm
20. Hydrolysis of one ATP molecule to ADP releases_calories of energy.
A) 730 B) 7,300
C) 68,600 D) 73,000
21. Which one of the following DNA duplex has highest melting temperature?
A) 5' ATGGCTCGT 3' B) 5' ATGGGCCCTG 3'
3' TACCGAGCA 5' 3' TACCCGGGAC 5'
C) 5' ATGA7ACTG 3' D) 5' GGCTGGAGA 3'
3' TACTATGAC 5' 3' CCGACCTCT 5'
22. Receptors for which of the following hormones are found in the cytoplasm of responsive cells?
A) Thyroid hormone and insulin B) Insulin and estrogen
C) Thyroid hormone and estrogen D) Glucagon and estrogen
23. The cooking time for food is reduced in a pressure cooker because
A) Heat is more evenly distributed in B) Boiling point of the water involved in the cooking space cooking is decreased
C) Boiling point of the water involved D) The higher pressure inside the in cooking Is increased cooker pulverizes the food material
24. The animals that are genetically constructed to differ at one particular locus are called as
A) Transgenic B) Chimeric
C) Hybrid D) Congenic
25. Sequencing and analysis of rRNA has divided the living world into three domains called
A) Bacteria, archaea & eukarya B) Archaea, eukarya & virus
C) Fungi, plants and animals D) Bacteria, archaea & plants
26. A process In which movement of a molecule across the membrane down its concentration gradient is coupled to the movement of a second molecule up its concentration gradient and across the membrane in opposite direction is called -
A) Active transport B) Symport
C) Uniport D) Antiport
28. Planarian use_ 27. The matrix of mitochondria contains A) FADH2 C) A high concentration of glucose for excretion A) Nephridia C) Uriniferous tubules |
B) Citric acid cycle intermediates D) Glycogen B) Flame cells D) Malpighian tubules |
29. The occurrence of tetratype in the acetomycete fungi is possible only if the crossing over occurred during the
A) G1 phase B) S phase
C) Two-strand stage D) Four-strand stage
30. In mammals, the diaphragm separates the
A) Peritoneal cavity from the thoracic ) Peritoneal cavity from pericardial cavity cavity
C) Thoracic cavity from the pericardial D) Thoracic cavity from the pelvic cavity cavity
31. Which one of the following metabolites is not directly produced in the hexose monophosphate shunt pathway?
B)
Gluconolactone-6-phosphate D) Erythrose-4-phosphate
B) Matrix of mitochondria D) Outer mitochondrial membrane
A) Fructose-6-phosphate C) Dihydroxyacetone phosphate
32. Cytochromes are found in
A) Cristae of mitochondria
C) Inner mitochondrial membrane
33. Tapeworms attach to the digestive lining of the host by means of their
A) Scolex B) Stylete
C) Proglottid D) Mastax
34. If the paternal chromosomes have alleles A, B, c and the maternal chromosomes have a, b, C - then the chromosomes that are not a product of crossing over are -
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A) A B c and a b C B) A b C and a B c
C) A b c and a B C D) A B C and a b c
35. Nondisjunction involving the X chromosomes may occur during oogenesis and produce two kinds of eggs. If normal sperms fertilize these two types, which of the following pairs of genotypes are possible?
A) XXY and YO B) XXY and XO
C) XX and XO D) XX and XY
36. Methionyl-transfer RNA is used for initiation of protein synthesis by which of the following?
A) Chloroplast B) Eukaryotic mitochondrial ribosomes
C) Bacterial ribosomes D) Eukaryotic cytoplasmic ribosomes
37. Which component in the viral envelope attaches the human deficiency virus (HIV) to host cells?
A) p24 B) pl8
C) gp41 D) gpl20
38. Which one of the following could be used to distinguish between an aldose and a ketose?
A) Fehling's reagent B) Tollen's reagent
C) Feulgen's reagent D) Br? water
39. Common method used for determination of the three dimensional structure of proteins is
A) Edman degradation B) X-ray crystallography
C) MALDI TOF analysis D) Two dimensional gel electrophoresis
40. Which one of the following is correct? A) Glycogen hydrolysis is promoted B) by the hormone glucagon C) Carbohydrates are absorbed D) primarily in the form of disaccharides |
Animal cells produce cellulase which hydrolyze cellulose Insulin has little effect on carbohydrate metabolism |
41. If a phosphodiester bond in one strand of double stranded circular DNA is
broken, the DNA is said to be
A) Nicked B) Digested
C) Cleaved D) Linearized
42. The first virus to be purified was
Influenza virus Smallpox
A) Tobacco Mosaic virus B)
C) Polio virus D)
43. The amino acid leucine has the following side chain.
A) CH3-CH(OH)- B) CH3-CH - (CH)2 -
C) (CH3)2 - CH - CH2 - D) CH3 - CH2 - CH - (CH3)
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44. Which one of the following Is WOT a part of the immune system?
A) Pancreas B) Thymus
C) Spleen D) Tonsil
45. Liebermann's reaction is used for detection of
A) aniline B) benzoic acid
C) phenol D) nitrobenzene
46. When an animal cell Is placed in 0.5 M sucrose solution, its volume does not alter. When the same cell is transferred to a 0.5 M NaCI solution, the volume of the cell will
A) Decrease B) Increase
C) Remain unchanged D) Increase and then decrease
47. Which one of the following is mismatched?
A) Matrix- extracellular material in B) Ligamentsbind muscles to bone connective tissue
C) Cardiac muscle cells-multipie D) Adipose cells- found in loose nuclei connective tissue
48. The nucleic acid which is highly modified by extensive methylation after synthesis is
A) hnRNA B) tRNA
C) rRNA D) mRNA
49. Which one of the following is an acidic amino acid?
A) Lysine B) Aspartic acid
C) Isoleucine D) Proline
50. Genetic recombination in bacteria occurs through the transfer of
A) Pili B) Gametes
C) Plasmids D) Endospores
51. The second messenger which plays a crucial role in regulating the synthesis and breakdown of glycogen in liver and muscle cells is
A) IP3 B) CAMP
C) DAG D) cGMP
52. What blocks myosin from binding to actin, when the muscle is at rest?
A) Acetylcholine B) Tropomyosin
C) ATP D) Troponin
53. Which one of the following is not a cancer drug?
A) Daunorubicln B) Cisplatin
C) Isoniazid D) Methotrexate
54. Isotypes refer to variation in the
A) Light chain variable region B) Heavy chain constant region
C) Light chain constant region D) Heavy chain variable region
55. When chromosome breakage occurs and the broken segment rotates by 180 degrees before reunion, the resulting chromosome aberration is known as
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A) Insertion B) Inversion
C) Frame shift D) Translocation
56. A common method for separating cell organelles and insoluble material from soluble proteins -
A) Filtration B) Differential centrifugation
C) Polyacrylamide gel electrophoresis D) Column chromatography
57. Cystic fibrosis is caused by _mutation.
A) Autosomal dominant B) Sex linked recessive
C) Autosomal recessive D) Sex linked dominant
58. In sensory neurons, stimuli are conducted through
A) Axons B) Cell body
C) Myelin sheath D) Dendrites
59. According to molecular definition of a gene, which one of the following is not a part of eukaryotic gene?
A) Promoter B) Poly (A) tail
C) Enhancer D) Polyadenylation signal
60. At room temperature formaldehyde changes into
A) Acetic acid B) Trioxane
C) Acetaldehyde D) Paraldehyde
61. Which one of the following is part of the gynoecium?
A) Carpel B) Filament
C) Stamen D) Sepal
62. The major class of insoluble fibrous protein present in the extracellular matrix and in connective tissue is
A) Cadherin B) Collagen
C) Actin D) Fibronectin
53. The following method helps in determining the genotype of an individual for a particular trait
A) Back cross B) Test cross
C) Monohybrid cross D) Dihybrid cross
54. The rhythmic beating of the heart is initiated by the
A) Sinoatrial node B) Purkinje fibers
C) Atrioventricular node D) Bundle of His
>5. Which one of the following is an innate immune cell type?
K) B lymphocyte B; T lymphocyte
C ) NKT cells D Macrophage
66. Which one of the following is not characteristic of members of the plant kingdom?
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A) Chlorophyll a B) Chlorophyll b
C) Chlorophyll c D) Carotenoids
67. Releasing hormones (TRH, GnRH etc.) in higher animals are synthesized and secreted by
A) Adenohypophysis B) Pars-intermedia
C) Neurohypophysis D) Hypothalamus
68. The neurotransmitter at the neuromuscular junction is-
A) Serotonin B) Acetyl choline
C) Dopamine D) Epinephrine
69. Which one of the following is not a primary alcohol?
A) Ethanol B) Isopropyl alcohol
C) Benzyl alcohol D) Methanol
70. Green algae, recently been investigated as food source in several nations is
A) Volvox B) Pseudomonas
C) Chlamydomonas D) Chlorella
71. The virus commonly used for the management of insect pests as well as a vector for production of recombinant proteins is
A) Baculovirus B) Adenovirus
C) Parvovirus D) Retrovirus
72. Two antagonistic hormones are-
A) MSH & TSH B) Oxytocin & Prolactin
C) Calcitonin & Parathormone D) ADH & GH
73. Which has the maximum percentage of Cl?
A) PVC B) BHC
C) Neoprene D) DDT
74. The inflammatory response includes all of the following except
A) Phagocytic attack B) Vessel constriction
C) Increased blood flow D) Temperature increase
75. Worlds natural gas reservoirs are primarily produced by
A) Archaebacteria B) Actinomyces
C) Primitive protists D) Anaerobic fungi
76. Components of animal cell cytoskeleton found in cilia and flagella that direct chromosomal movement during cell division are
A) Microfilaments B) Microtubules
C) Intermediary filaments D) Microtubules and microfilaments
77. Solid CO2 is an example of A) Ionic crystal B) D) C) Molecular crystal 78. The following are epimers of glucose A) Galactose and fructose B) C) Sucrose and fructose D) |
Covalent crystal Metallic crystal Mannose and fructose Mannose and galactose |
79. Enzymes from the following organelle are involved in the oxidation of fatty acids, but the released energy is not used for ATP synthesis
A) Ribosomes B) Lysosomes
C) Mitochondria D) Peroxisomes
80. While most of the insects have four wings, the following have only two
A) Housefly B) Honeybee
C) Butterfly D) Cockroach
81. Enzyme produced in the kidney, angiotensinogen present in the blood- A) Angiotensin B) C) Renin D) |
which catalyzes the cleavage of Bradykinin Kynurenine |
82. Cerebellum regulates B) D) A) Body temperature C) Sleep*wake cycle |
Learning and memory Movement and balance |
83. If radioactive sulphur is added to culture medium of E. coli, the radioactive label after 48 hours will be localized in
A) DNA B) RNA
C) Phospholipid D) Enzymes
84. Vertebrate lungs are derived from
b) Ectoderm ) Mesoderm
C ) Epiderm ) Endoderm
85. Glucokinase
A) Is widely distributed in most of the B) Is inhibited by glucose-6-phosphate mammalian tissues
C) Has high Km for glucose D) Catalyzes a reversible reaction
86. Humans can digest starch and not cellulose. Both of them contain monomeric glucose units. Starch is digested due to specificity of the intestinal enzymes for
A) a l->4 linkage B) P l->4 linkage
C) o l->6 linkage D) p l->6 linkage
87. Drugs that prevent the formation of bacterial cell wall are
A) quinolones B) aminoglycosides
C) beta-lactams D) Tetracycline
88. Heat shock proteins, originally identified as proteins expressed in response to stress, also function as -
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A) Molecular chaperones, which assist B) GTPase activating proteins in de novo protein folding C) Protein kinase D) Proteases degrading ubiqultln-tagged
proteins
89. When a lead storage battery is discharged
A) Sulphuric acid is consumed B) S02 is evolved
C) Lead is formed D) Lead sulfate is consumed
90. The genome of an organism contains 20% adenine residue. Which one of the following statement is correct?
A) G + C content is 20% B) G + C content is 40%
C) G + C content is 60% D) G + C content is 80%
91. If one mL of 0.01 M HCI is diluted to 100 mL at 25 C, what will be the pH of the resulting solution?
A) 7 B) 5
C) 4 D) 2
92. Which one of the following pathway is very active in the tissues involved in lipogenesis and nucleic acid biosynthesis?
A) Glycolysis B) 3 oxidation
C) HMP shunt pathway D) TCA cycle
93. Which one of the following is a human cell line?
A) Hela B) BHK-21
C) CHO D) Sf-9
94. When a gasoline is given "octane number" 80, it means it contains
A) 80% iso-octane B) 80% octane
C) 20% iso-octane D) 20% benzene
95. The bacteria which utilize C02 as the sole carbon source and obtain energy by oxidation and reduction of inorganic substances are called as
A) Chemolithotrophs B) Photoheterotrophs
C) Photoautotrophs D) Chemoheterotrophs
96. Human albinism is caused by recessive gene 'a'. A child has albinism, although none of the parents are affected. What is the genotype of parents?
A) Aa and Aa B) Aa and AA
C) Aa and aa D) AA and AA
97. Viral replication within cells is inhibited by
A) IFN-y B) IL-1
C) IL- 4 D) TNF- a
98. In the mitochondrial genome, the stop codon is
A) UAA B) AGA
C) UUU D) UGA
99. Which one of the following is a polyatomic cation?
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A) Mg?+ B) OH'
C) NH4+ D) Cu2+
100. Human embryonic stem cells are commonly derived from
A) Cord blood cells B) Trophoblast
C) Complete blastocyst D) Inner cell mass (ICM)
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