Kerala University 2009 B.Pharm Third Year ,,PHARMACEUTICAL CHEMISTRY – V, (Chemistry of Natural Produ - Question Paper

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Name : ..........................................

Third Year B.Pharm. Degree Examination, April 2009,PHARMACEUTICAL CHEMISTRY – V
(Chemistry of Natural ProduTime : three Hours Max. Marks : 80cts)

Instructions: 1) ans part A and part B in separate ans books.
2) Answer any 4 ques. from every part.
3) Question No. I and ques. No. VI are compulsory.
4) All ques. carry equal marks.

part – A

I. Explain the subsequent :

a) Diel's hydrocarbon

b) Nucleotides

c) Hofmann exhaustive methylation

d) Special isoprene rule

e) Inter relationship ranging from ceffeine, theophylline and theobromine.

II. How naturally occurring steroidal hormones are classified ? Outline the synthesis of testosterone. elaborate anabolic steroids ?

III. Write notes on :

a) Oral contraceptives.

b) Synthetic non steroidal oestrogenic compounds.

IV. explain briefly the chemistry of Terpenes. discuss the structure and constitution of Alpha terpeniol. What is the interrelationship ranging from limonene, dipentene, Alpha terpeniol terpene hydrate, cineole and carvone ?

V. Outline the synthesis of : a) Vitamin C

b) Ephedrine c) Uric acid
d) Cortisone.
P.T.O.


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part – B

VI. provide the method of isolation, structural features and chemistry of cholesterol.

VII. Write notes on :

i) Chemistry and biological importance of Insulin

ii) Constitution and synthesis of Vitamin D.

VIII. elaborate glycosides ? provide the chemistry and synthesis of Amygdalin.

IX. Write notes on :

i) Saponins

ii) Prostaglandins.

X. provide the chemical structure and biological importance of the subsequent :

i) Riboflavine

ii) Digoxin

iii) Betamethesone

iv) Ergosterol.

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