Jawaharlal Nehru Technological University Anantapur 2009-2nd Sem B.Tech Information Technology Code No: R5421205 IV ester(R05) Advanced Supplementary s, BIO-INFORMATICS - Question Paper

Code No: R5421205
IV B.Tech. II Semester(R05) Advanced Supplementary Examinations, July 2009
BIO-INFORMATICS
(Information Technology)
Time: three hours Max Marks: 80
ans any 5 ques.
All ques. carry equal marks

1. (a) explain in detail the elementary commands.
(b) Expand and discuss FTP.
(c) discuss in detail info theory primer.
2. (a) explain about homology theories.
(b) discuss Charles Darwin theory of Natural selection.
(c) Compare Sir Richard Owen and Alfred Russel Wallace theories of homology.
3. (a) What is DNA mapping and Sequencing ? Add a note on their importance.
(b) discuss in detail Map alignment.
(c) define Sanger method of DNA sequence.
4. (a) Compare and contrast local alignment and global alignment.
(b) explain in detail the Heuristic alignment algorithms.
(c) discuss PAM and BLOSUM.
5. (a) elaborate databases ? Add a note on their importance in applied sciences.
(b) Protein Data Bank.
(c) Write about NCBI and EMBL.
6. (a) explain the organization and management of databases.
(b) Swissprot.
(c) De¯ne PIR.
7. (a) Write the importance of Biochemical databases?
(b) discuss EXGESCY.
(c) De¯ne BRENDA.
8. (a) What is multiple sequence alignment? Write on Clustal W.
(b) What is Dendrogram? Write its importance in computational biology.
(c) What is Phylogenetic analysis and elaborate the different methods followed?

Earning:   Approval pending.