Biju Patnaik University of Technology 2008-6th Sem B.Pharm Pharmacology-II - Question Paper
Time: 3 Hours
Answer Question No. 1 which is compulsory and any five from the rest.
The figures in the right-hand margin indicate marks.
1. Answer the following questions : 2*10
(a) Comment on the simultaneous administration of digitalis glycosides and thiazide diuretics.
(b) Name two respiratory stimulant drugs.
(c) Give two examples of class III antiar-rhythmic drugs.
(d) Give two examples of leech products which can be used as anticoagulant.
(e) What are the symptoms of Prinzmetals angina ?
(f) What will happen if a patient takes aspirin simultaneously with warfarin ?
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(g) Name two preparations used in the bioassay of acetylcholine.
(h) Write the mechanism and use of monte-lukast.
(i) Name the disease in which vasopressin can be used.
(j) Write the use of streptokinase.
Define Bioassay. What are the advantages and disadvantages of Bioassay. Describe the different methods of Bioassay for agonists.
1+2+7
3. Classify antihypertensive drugs with examples. Write the mechanism and side effects of Captopril and Amlodipine. 5+2.5x2
4. Write the mechanism and therapeutic uses of
(any two) : 5x2
(a) Organic nitrates
(b) (3 blockers
(c) Thiazide diuretics.
5. Classify the drugs used in the treatment of Bronchial asthma. Write short notes on Glucocorticoids and Salmeterol. 5+2.5x2
6. Define and classify anticoagulants. Discuss the mechanism and side effects of Warfarin.
5+5
7. Define Autacoids. How are they different from hormones ? Classify Autacoids. Write the pharmacological actions of histamine. 1 +1 +3+5
(a) Codeine
(b) Bradykinin
(c) Iron preparations
(d) Vitamin K.
PH. 6.9 4 -C
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