Vinayaka Missions University 2009 B.E Bioinformatics / - exam paper

SI. No. E4957 Sub. Code:3540539
B. E. DEGREE exam
Fifth Semester
BIO INFORMATICS
MOLECULAR EVOLUTION AND PHYLOGENY
Time: 3 Hours Maximum: 80 Marks
ans ALL ques.
PART-A (10 x two = 20 Marks)

1. What is gene frequency?
2. What is gene duplication?
3. Define synonymous mutation.
4. What is non-synonymous region?
5. What are the various kinds of Phylogenetic trees?
6. What does the terminal and internal nodes represent?
7. What is distance correction?
8. What is the principle behind maximum parsimonious method?
9. What is MOLPHY?
10. Name few packages of phylip.


PART-B (5 x 12 = 60 Marks)

11. a) provide detailed account on the population genetics
OR
b) describe recombination. discuss its role in evolution.
12. a) define in detail about molecular clock
OR
b) How is genes functions change by recombination? discuss
13. a) provide detailed account on Phylogenetic trees.
OR
b) Distinguish ranging from Phylogram & Cladogram
14. a) How is distance method helping us to construct a phylogenetic tree?
OR
b) What is substitution? discuss its different kinds with suitable example.
15. a) discuss in detail about application of phylogenetics.
OR
b) Point out the importance of phylogenetic analysis.
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Earning:   Approval pending.