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Manipal University 2009 M.Pharm Part-I -university question paper

Saturday, 26 January 2013 04:30Web


Manipal University
M.Pharm Part-I Degree Examination- May/June 2009
Subject: Industrial Microbiology (PBT 601)
Specialisation: Pharmaceutical Biotechnology

Reg. No.

MANIPAL UNIVERSITY M. PHARM. PART-I DEGREE EXAMINATION - MAY/JUNE 2009 SUBJECT: INDUSTRIAL MICROBIOLOGY (PBT 601)

SPECIALIZATION: PHARMACEUTICAL BIOTECHNOLOGY

Thursday, May 28, 2009

Time: 10:00-13:00 Hrs._Max. Marks: 100

jsS Answer all the questions.

IA.    Draw neat labeled diagram of a typical bacterial cell and discuss the structures external to cell wall.

IB.    Explain the alternative pathways to glycolysis for oxidation of glucose by bacteria. Differentiate between anabolism and catabolism.

(10+10 = 20 marks)

2A. Enlist any four important characteristics of viruses and discuss the replication process of bacteriophage.

2B. What is fungal dimorphism? Explain the different stages in formation of sexual_spores.

2C. With a neat labeled diagram, explain the formation of bacterial endospore.

(10+5+5 = 20 marks)

3A. List out the criteria to design a medium for industrial fermentations and outline the salient features for media formulation.

3B. Draw comparison of batch and continuous culture for biomass productivity.

(10+10 = 20 marks)

4A. Discuss the production of streptomycin.

4B. Discuss the production of L- Glutamic acid emphasizing biosynthesis and briefly outline the production process.

(10+10 = 20 marks)

5A. Explain how does numerical aperture influence resolving power and suggest the ways to increase numerical aperture.

5B. Enlist the significant pathogenic ChlamyJiae and write briefly the unique life cycle of Chlamydia.

5C. Write short note on Lipases.

5D. Write any two commercial processes of steroidal conversions mentioning the nature of reaction, substrate, product and microorganism.

(5+5+5+5 = 20 marks)

PBT 601    Page 1 of 1







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