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Manipal University 2009 M.Pharm Part-I - university paper

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Manipal University
M.Pharm Part-I Degree Examination- May/June 2009
Subject: Bioprocess Engineering (PBT 602)
Specialisation: Pharmaceutical Biotechnology

MANIPAL UNIVERSITY M. PHARM. PART-I DEGREE EXAMINATION - MAY/JUNE 2009 SUBJECT: BIOPROCESS ENGINEERING (PBT 602) SPECIALIZATION: PHARMACEUTICAL BIOTECHNOLOGY Friday, May 29, 2009

Reg. No.


Time: 10:00-13:00 Hrs.

Max. Marks: 100


j& Answer all the questions.

1 A. Draw a neat labeled diagram of an Industrial fermenter and discuss temperature control.

IB. Discuss Waldhof-type fermenter and Acetators and Cavitators.

(10+10 = 20 marks)

2A. What are the methods for sterilizing air? Discuss the design of depth filters.

2B. Explain pseudo plastic rheology of fermentation broth with examples.

(10+10 = 20 marks)

3A. Discuss the principle behind the design of rotary drum filter. Explain its working and application.

3B. What are the mechanisms involved in adsorption? Give the analysis of adsorption phenomena for a packed bed column.

(10+10 = 20 marks)

4A. Explain the dynamic method of gassing out for determination of Ka. Mention the relationship between power consumption and Ka.

4B. Explain the construction and working of a spray dryer with the help of a neat labeled diagram.

(10+10 = 20 marks)

5. Write short notes on:

5A. Magnetic drives 5B. Thermistors 5C. Scale down 5D. Electrophoresis.

(5><4 = 20 marks)



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