Janardan Rai Nagar Rajasthan Vidyapeeth 2006 B.Tech Biotechnology CELL AND MOLECULAR BIOLOGY - Question Paper

Model Question Paper

BSBT9- CELL AND MOLECULAR BIOLOGY

Time : 3 hrs Maximum marks : 75

 

Instruction:

1. Question paper is divided into Group A, Group B and Group C

2. Each Group is 25 Marks

3. Figure to the right in bracket indicates marks.

4. Good Handwriting is expected

5. Assume suitable data if necessary.

 

Group A (25 Marks)

 

Answer any three questions (Question 1 is compulsory)

	(5)

 

(10)

Q.1 Explain cells obey the laws of thermodynamics ?

(10)

Q.2 What induce supercoiling of DNA? Can we induce formation of supercoil by joining the ends of a linear DNA and then twisting the circle ?

(10)

Q.3 Explain oxidative phosphorylation and what are the theories of oxidative

Phosphorylation ?

 

Q.4 Explain in detail how Glycogen is synthesized ?

Q.5 Write Explainatory notes on :-

1. Spermatogenesis 2. Fertilization

Group B (25 Marks)

 

(5)

Answer any three questions (Questions 6 is compulsory)

 

Q.6 What are the Enzymes used in DNA replication ?

(10)

Q.7 Explain the factors influencing cell differentiation ?

(10)

Q.8 What is synapse ? Describe the mechanism of synaptic transmission ?

 

(10)

Q.9 What is bioinformatics ? What are the objectives of bioinformatics ? What are

the challenge for Bioinformatics ?

	(10)

 

Q.10 Write about agents causing damage to DNA ?

 

 

 

 

 

 

 

 

 

Group C (25 Marks)

All Questions are Compulsory.

Q.11 Fill in the blanks ( each question carry 2 marks)

1. Modulation in differentiated cell may takes place in response to extracellular factors like ______ ,

pH and temperature.

2._________ carry impulses to the effectors, such as muscles glands etc.

3. The eukoryotic ribosomes has sedimentation coefficient of 80S, comprising of small 40S and a

large _________

4. The sum of purine residue equals the sum of pyrimidine residues. This was known as _______

5. DNA duplex uncoiled shows complementary anti parallel strands having ______ polarity.

 

Q.11 Multiple choice question. (Each question carry 2 marks)

1. The membrane potential of the Resting cell is about _______

a) +35 mV b) -50 mV c) -70mV d) +40 mV

2. ________ is an enzyme which joins the ends of two DNA.

a) DNA pol II b) DNA ligase c) DNA pol III d) DNA pol I

3. __________ representing reformation of nucleus and Cytokinesis

a) Anaphase b) Prophase c) Metaphase d) Telophase

4. The production of chemical substances by cell, which inhibit the rate of mitosis these are

called as _________ .

a) Chalones b) Fission c) Fusion d) Meiosis.

5. The paired chromosomes begin to pull apart, but they do not separate completely since they are

held together at the points of interchange . It is ___________

a) Diakinesis stage b) Diplotene stage c) Telophase stage d) Metaphase Stage

 

Q.11 True or false (each question carry 1 marks).

1. Addition or removal of groups without involving water is done by Enzyme hydrolase.

2. The Acetyl CoA, instead of undergoing oxidation through the citric acid cycle, becomes

reduced to fatty acid by action of NADPH.

3. The two polynucleotide chains that runs in opposite direction are said to be anti-parallel

to each other .

4. DNA synthesis does not begin when DNA polymerase III joins with primosome.

5. Filling up of gaps created by exision of primers is by Deoxyribonucleotide residue.

 

 

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