Magadh University 2009 M.B.B.S Pharmacology -1 - Question Paper

(c) Betahistine in vertigo
(d) Adrenaline as anaphylacting agent

2005(I)
1. define muscarinic and nicotinic actions of Acetylcholine and state the pharmacological actions and therapeutic uses of atropine. (6+5+4=15)
2. Write short notes on any 3 of the subsequent : (5*3=15)
(a) Therapeutic drug Monitoring
(b) 2nd Generation Antihistaminics
(c) Erythropoietin
(d) Lithium Carbonate
3. What is the mechanism of action of the subsequent : (2.5*4=10)
(a) Thiazide Diuretics
(b) Valproic Acid
(c) Ethyl Alcohol
(d) Leukotriene Antagonist

2004(I)
1. Classify Diuretics. explain mechanism of action and therapeutic uses of Frusemide. (4+5+5=14)
2. Write short notes on : (5+5+5=15)
(a) Therapeutic Index
(b) Salbutamol
(c) Ketamine
3. explain the mechanism of action of : (2.5*4=10)
(a) Aspirin
(b) Morphine as analgesic
(c) Theophylline as bronchodilator
(d) Bromocriptine as antiparkinson drug

2003(I)
1. Classify antiparkinson drugs and explain mechanism of action and adverse effect of Levodpa. (5+5+5=15)
2. Write short notes on : (5+5+5=15)
(a) Preanaesthetic medication
(b) Sodium cromoglycate
(c) Neurohumoral transmission
3. explain the mechanism of action of : (2.5*4=10)
(a)
(b) Chlorothiazide
(c) Piroxicam
(d) Lithium carbonate

2002(I)
1. Classify general anaesthetics. provide an account of inhalation anaesthetic drugs. (5+10=15)
2. Write short notes on : (5*3=15)
(a) Microsomal Enzyme inductions
(b) Spinal anaesthesia
(c) Drug therapy of migraine
3. elaborate the mechanism of action of : (2*5=10)
(a) Theophylline
(b) Acetozolamide
(c) Dopamine
(d) Ticlopidine
(e) Neostigmine in myasthenia gravis

2001(I)
1. Classify antiepileptic drugs. explain the pharmacology of drugs used in petit mal epilepsy. (15)
2. Write short notes on any 3 of the subsequent : (5*3=15)
(a) Half-life of drug
(b) Primary Prostaglandins
(c) ACE inhibitors
(d) Heparin
3. provide the accurate ans : (1*10=10)
(a) Name 1 selective B1 adrenergic receptor agonist.
(b) Atropine is contraindicated in chronic simple glaucoma. 'True' or 'False'.
(c) The daily requirement of iron in an adult male is ……….
(d) Name on mood stabilizing drug.
(e) Name on potassium sparing diuretic.
(f) Antiemetic action of metoclopramide is due to blockade of …………….. Receptor.
(g) The drug of option to lower serum cholesterol is …………….
(h) Name 1 potassium channel blocker.
(i) The drug of option in motion sickness is …………...
(j) Name 1 2nd generation H1 receptor antagonist.
2001(New)
1. Classify anticholinergic drugs. explain their therapeautic uses and adverse effects. (15)
2. Write short notes on any 3 of the following: (5*3=15)
(a) Expectorants
(b) Potassium sparing diuretics
(c) Microsomal enzyme induction.
(d) Antiplatelet drugs
3. Objective (1*10=10)
1999(I)
1. Classify antiepileptics. explain the pharmacological characteristics, adverse effects and therapeutic uses of phenytoin 'OR'
Name the drugs used in the t/t of congestive cardiac failure. explain the mechanism of action, therapeutic uses and adverse
Effects of ACE inhibitors. (6+4+3+3=16)
2. Write short notes on: (3*4=12)
(a) Atropine substitutes.
(b) Half life
(c) Alfrazolam
(d) Methadone
3. explain the mechanism of action of : (3*4=12)
(a) Glyceryl trinitrate in angina pectoris
(b) Methyldopa in Hypertension
(c) Penicillin as antimicrobial agent
(d) Lignocaine as anti-arrythmic agent

Earning:   Approval pending.