Magadh University 2009 M.B.B.S Pharmacology -1 - Question Paper

Pharmacology - PAPER-1

2009 (A)
1. Classify anti epileptic drugs. explain the pharmacodynamics, pharmacokinetics, adverse effects, drug interactions and uses of phenytoin. (16)
2. describe catecholamines. explain the pharmacological actions and therapeutic uses of adrenaline and nor-adrenaline. (12)
3. Write short notes on the following: (3*4 = 12 )
(a) Treatment of myasthenia gravis.
(b) Buspirone
(c) Lignocaine
(d) Ketamine

2009 (I)
1. define pathophysiology of Parkinson's disease. Classify drugs used in the treatment and explain about levodopa. (5+5+5 = 15)
2. ans the following: (5*3=15)
(a) discuss the mechanism of action of timolol in glaucoma.
(b) discuss the mechanism of action of H1 receptor antagonist in treating allergic reaction.
(c) discuss the mechanism of action of adrenaline in anaphylactic shock.
3. Write short notes on any 2 of the following: )5*2=10 )
(a) Drug treatment of myasthenia gravis
(b) Desferroxamine
(c ) Low mol. Wt. Heparin

2008(I)
1. Classify Nonsteroidal anti-inflammatory drugs. Write down the pharmacological action and therapeutic uses of Aspirin. (5+5+5=15)
2. Write the mechanism of actions of any 3 of the following: (3*5=15)
(a) Morphine in left ventricular failure
(b) Heparin as anticoagulant
(c ) Pilocarpine in glaucoma
(d) Phenytoin Sodium in grandinal epilepsy
3. Write short notes any two: (2*5=10)
(a) Tricylic antidepressants
(b) Leucotriene Antagonists
(c) Allopurinol

2007(I)
1. Classify bronchodilators. explain their merits and demerits in the treatment of asthma. (5+5=10)
2. Write short notes on any 3 of the following: (3*5=15)
(a) Management of organophosphorus poisoning
(b) Enzymes and drug actions
(c) Uses and contraindications of morphine
(d) Monoamine oxidase inhibitors
2. Write short notes on any 2 : (2*5=10)
(a) Spironolactone.
(b) Uses and contraindications of B-blockers
(c ) Sodium valproate

2006(I)
1. Classify antidepressant drugs. Write in brief, pharmacological action and clinical uses of Tricyclics. (5+5+5=15)
2. Write short notes on the subsequent : (5*3=15)
(a) Enzyme Induction
(b) Levodopa
(c) Ketamine
3. Write pharmacological basis of the subsequent : (2.5*4=10)
(a) Dopamine in Hypovolaemic shock
(b) Pralidoxime in organophosphorus poisoning

Earning:   Approval pending.