Magadh University 2009 M.B.B.S Pharmacology -2 - Question Paper

3. Write briefly on : Cholestyramine OR Levamisole (4)

Sec A
1. discuss the pharmacological basis of t/t of : (a) Acute congestive glaucoma (b) Migraine (c) Myocardial Infarction (d) Acute bronchial asthma (20)
2. Write briefly on : (a) Prazosin (b) Lignocaine (c) Oral anticoagulant (d) ACE inhibitors (12)
3. discuss why : (8)
(a) Morphine is used in cardiac asthma and not in bronchial asthma.
(b) In barbiturate poisoning forced alkaline diuresis is the treatment.
(c) Benzhexol not levo-DOPA is use in durg-induced parkinsonism.
(d) Benzodiazepines have changed barbiturate for sedative/hypnotic effects.

1999(II) Sec B
1. Enumerate the drugs used in the t/t of Amoebiasis. explain the mechanism of action, toxic effects and clinical uses of Metronidazole. (6+3+3+4=16)
2. Short notes on : (a) Bio-availability (b) Omeprazol (c) Tocolytic agents (d) Calcitonin (3*4=12)
3. Disucss the modes of action of the subsequent drugs : (3*4=12)
(a) Radioactive iodine in hyperthyroidism
(b) Chloroquine in malaria
(c) INH in tuberculosis
(d) Amphotericin B in kala-azar

Sec A
1. Enumerate the drugs used in t/t of anxiety. explain the mechanism of action, therapeutic uses and adverse effects of diazepam. (5+5+3+3=16)
2. discuss why : (3*4=12)
(a) Clofibrate is used in hyperlipidemia.
(b) Adrenaline is the drug of option in anaphylaxis.
(c) Terbutaline is preferred to isoprenaline in t/t of bronchial asthma.
(d) Levodopa is combined with carbidopa in the t/t of parkinsonism.
3. Short notes on : (a) Desferrioxamine (b) Pirenzipine (c) Morphine (d) Neostigmine (3*4=12)

1998(I)Sec A
1. Classify antihypertensive drugs mentioning their importnant pharmacological actions and side effects. (16)
2. Write briefly on : (a) Heparin (b) Bromhexine (c Pre-anaesthetic agents (d) Organophosphorous compounds (12)
3. explain the mechanism of action of subsequent : (12)
(a) Loop diuretics (b) Digitalis (c) Aspirin as antiplatelet agent (d) Dilantin

Sec B
1. Classify drugs used in t/t of tuberculosis. define the various drugs regimens for the t/t of tuberculosis. Write briefly their mode of actions and important toxicities.
2. describe these terms : (a) Tolerance (b) Antiemetics (c) Antibiotics (12)
3. Comment on the subsequent : (12)
(a) Chelating agents
(b) Therapeutic index
(c) Antidiarrhoeal agents
(d) Oral antidiabetics

1998(II)Sec A
1. discuss the pharmacological basis of t/t of :
(a) Angina pectoris (b) Organophosphorous poisoning (c) Myasthenia gravis (d) Idiopathic parkinsonism
2. Write briefly on : (a) Streptokinase (b) Captopril (c) Valproic acid
3. Enumerate : (a) 2 important contraindications of morphine (b) 2 important contraindications of Aspirin.
(c) 2 drugs indicated for attack of bronchial asthma (d) 2 clinical conditions for which Furosemide is indicated (e) 2 adverse effects of tubocurarine.

Sec B
1. Outline the chemotherapy of any 4 of the subsequent : (20)
(a) Pulmonary tuberculosis in elderly male.
(b) Pseudomonal UTI in pregnancy.
(c) Subacute bacterial endocarditis.
(d) Enteric fever
2. Short notes on : (16)
(a) Metronidazole
(b) 3rd generation cephalosporins
(c) Therapeutic index
(d) T/T of thyroid storm
3. Write briefly on : T/T of Duodenal ulcer OR Contraindication of glucocorticoids. (4)

1997(I)
1. Classify drugs used in kala-azar. define their modes of actions and toxicities. (4+4+4=12)
2. define : (a) Role of estrogen and progesterone as contraceptive agents.
(b) Calcitonin in Paget's disease of bone (c) Choloroquine in malaria (4+4+4=12)
3. Comment on : (a) Superinfection (b) Ulcer protective agents (c) Vaccine as preventive agent (d) Desferrioxamine in iron poisoning. (4*4=16)

Earning:   Approval pending.