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Veer Narmad South Gujarat University 2011-2nd Year B.Pharm SB-1155 PH-205 Pharmacology - 1 a - Question Paper

Saturday, 27 April 2013 05:40Web



SB-1155

Second Year B. Pharm. Examination March / April - 2011 PH-205 : Pharmacology-I

(Biochemistry & Pathophysiology)

Time : 3 Hours]

[Total Marks : 70


Instructions :

(1)

Seat No.:


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Fillup strictly the details of signs on your answer book.

Name of the Examination :

S. Y. B. Pharm.

Name of the Subject:

PH-205 : Pharmacology-1

-Subject Code No.:

1

1

5

5

-Section No. (1,2,.....): 1&2

(2)    Attempt all questions.

Student's Signature


(3)    Answer each section in separate answer book and tie them separately.

(4)    Figure to right indicate marks.

SECTION - I

1    Attempt any five questions :    10

(1)    Enumerate inhibitors of respiratory chain.

(2)    Explain regulation of gluconeogenesis.

(3)    Write biochemical functions of iron.

(4)    Give significance of uronic acid pathway.

(5)    Explain sulphate reduction.

(6)    Explain term bioenergetics.

(7)    Describe carnitine transport system.

2    Attempt any four questions :    16

(1)    Differentiate between competitive and non-competitive enzyme inhibition.

(2)    Explain the phathophysiology of angina pectoris.

(3)    Explain the factors affecting the enzyme activity.

(4)    Write note on oxidative phosphorylation.

(5)    Discuss biochemical importance of fructose and galactose metabolism.

(6)    Role of vitamins in citric acid cycle.

3 Attempt any three questions :    9

(1)    Discuss function of respiratory check.

(2)    Write note on free redical induced cell injury.

(3)    Explain etiopathogenesis of peptic ulcer.

(4)    Describe the role of enzyme and isoenzyme in various disorders.

(5)    Differentiate essential amino acid and nonessential amino acids.

SECTION - II

4    Attempt any eleven questions :    11

(a)    Define : (any six)

(i)    Chemotaxis

(ii)    Metabolism

(iii)    Anabolism

(iv)    Healing

(v)    Atherosclerosis

(vi)    Gluconeogenesis

(vii)    Atrophy

(viii)    Hypertension.

(b)    Attempt any five :

(i)    Enlist the function of cholesterol.

(ii)    Explain CCF.

(iii)    Give the structure of : Ascorbic acid, Cholesterol.

(iv)    Name of component of the respiratory chain.

(v)    Enumerate inflammatory mediators.

(vi)    Give reversible kinase reaction involved in glycolysis.

5    Attempt any three questions :    12

(1)    Explain the pathophysiology of atherosclerosis.

(2)    Explain glycogenolysis and its regulation.

(3)    Explain clinical and diognostic significance of enzymes.

(4)    Explain uric acid synthesis and its biochemical importance.

(5)    Describe pathophysiology of hypertension.

6    Attempt any two :    12

(1)    Draw TCA cycle and its energetic and regulation.

(2)    Define enzyme. Describe mechanism of action of enzyme activity.

(3)    Write pathophysiology of rheumatoid arthritis.

SB-1155]    2    [ 400 ]







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