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Veer Narmad South Gujarat University 2011-3rd Year B.Pharm SB-1161 PH - 301 Pharmaceutical Microbiology a - Question Paper

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SB-1161

Third Year B. Pharm. Examination March / April - 2011 PH - 301 : Pharmaceutical Microbiology

Time : 3 Hours]    [Total Marks : 70

Instructions

(1)_

Seat No.:


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Fillup strictly the details of signs on your answer book.

Name of the Examination :

T. Y. B. Pharm.

Name of the Subject:

PH - 301 : Pharmaceutical Microbiology

Student's Signature


-Subject Code No.:

1

1

6

1

-Section No. (1,2,.....): 1&2

(2)    The paper consists of two sections.

(3)    Each sections carry equal marks.

(4)    Figures to the right indicate marks.

(5)    All questions are compulsory.

(6)    Draw a neat and laballed diagram wherever necessary.

(7)    Both the sections must be written in separate answer books.

SECTION - I

1    Attempt the following questions : (any five)    10

(a)    Describe Kochs postulates.

(b)    Discuss in brief endosymbiotic theory.

(c)    Describe Bacterial cell division in brief.

(d)    Discuss briefly Haeckels Kingdom of Protista

(e)    Discuss life cycle of virus.

(f)    Explain in brief differential media with suitable example.

(g)    Discuss sporogenesis.

2    Answer the following questions : (any four)    16

(a)    Describe in detail Bacterial Growth Curve.

(b)    Describe methods for preservation of bacterial cultures.

(c)    Discuss the cultivation of viruses.

(d)    Discuss about the Nutritional requirements of bacteria.

(e)    Discuss briefly special staining techniques.

(f)    Explain the morphology of spirochetes in detail.

3    Write a short note on : (any three)    9

(a)    IgG

(b)    Applied areas of microbiology

(c)    Numerical Taxonomy

(d)    Bacterial cell wall

(e)    Microbial Spoilage.

SECTION - II

4    Define the following : (any eleven)    11

(a)

Protoplast

(b)

D-value

(c)

% G+C content

(d)

Endotoxin

(e)

Glycocalyx

Allergen

(g)

Lysogeny

(h)

Facultative anaerobe

(i)

Magnetosome

(j)

Terminal sterilization

(k)

Interferon

a)

Sterility assurance level

(m)

Mycelium

(n)

Actionmycetes

(o)

Bioburden.

5    Write short note on : (any three)    12

(a)    Moist Heat Sterilization

(b)    Diagnostic tests for Tuberculosis and typhoid

(c)    Biological Indicators

(d)    Plasma protein fractionation

(e)    Portal of entry for pathogen.

6    Answer in detail on following : (any two)    12

(i)    Differentiate between Prokaryotes and Eukaryotes

(ii)    Describe Physical and Chemical Methods of disinfection

(iii)    Discuss about Dextran as a Plasma substitute.




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