Veer Narmad South Gujarat University 2011-4th Year B.Pharm SB-1172 PH- 402 Pharmaceutics - 6 a - Question Paper
SB-1172
Final Year B. Pharm. Examination March / April - 2011 PH-402 Pharmaceutics : Paper - VI
(Pharmaceutical Technology and Industrial Pharmacy)
[Total Marks : 70
Time : 3 Hours]
Instructions :
(1)
N Seat No.:
6silq<3i Puunkiufl [qaim SuwiA u* qsq <KH=fl. Fillup strictly the details of signs on your answer book.
Name of the Examination :
Final Year B. Pharm.
Name of the Subject:
PH-402 Pharmaceutics : Paper-6
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-Subject Code No.: |
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-Section No. (1,2......): 1&2 |
(2) Answer and submit both sections separately.
(3) Figures to the right indicate marks.
1 Attempt any FIVE of the following :
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(1) Classify pharmaceutical tablets according to their routes of administration.
(2) Enumerate the various sources of contamination for parenteral dosage form.
(3) Write importance of HLB on stability of emulsion.
(4) Write various selection criteria for tablet diluents.
(5) Explain the term Quality assurance and Quality control.
(6) Why is shear plane of electric double layer considered as true surface of drug in dispersions ? What is its effect on stability of dispersion ?
(7) Explain Disintegration test of tablets.
(8) Write short note on LAL test.
2 Attempt any FOUR of the following :
(1) Write a note on dispersible tablets.
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(2) Explain quality control tests for tablets.
(3) Write a note on evaluation of suspensions.
(4) Enlist methods for preparation of microencapsules and discuss applications of microencapsulation.
(5) Write a short note on evaluation of aerosols.
(6) Classify semi-solid dosage forms. Write a note on formulation and packaging of semi solid dosage forms.
3 Attempt any THREE of the following : 09
(1) Describe the principal ingredients used in formulation of semisolids dosage forms.
(2) Differentiate the hard gelatin capsules from soft gelatin capsules. Briefly discuss the gelatin specifications required for capsule manufacturing.
(3) Write a note on additives used in ophthalmic preparations.
(4) Write a note on pharmaceutical imperfections observed on coated tablet.
1 Attempt any ELEVEN of the following :
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(1) Which manufacturing method is preferable to prepare Paracetamol Tablets ? Justify the answer.
(2) Enlist film defects in tablet coating.
(3) Write suitable examples of Diluents and Lubricants.
(4) Enlist the different tests for rubber closures.
(5) Give function and examples of disintegrants used in tablet dosage form.
(6) Give four examples of solubilizers in liquid dosage forms.
(7) Is there any difference between overages and overfill volume. What are the reasons to add overages and overfill volume ?
(8) Write chemical name of Propellant 114.
(9) Explain with examples : glidants and anti adherent.
(10) Write the properties of WFI.
(11) Write down chemical reaction involved between alcohol and aluminum container ?
(12) Define coarse powder and fine powder as per IP 2007.
(13) What do you mean by "Wet granulation technique in tablet preparation"?
(14) Give the full form of "SOP" and "HLB value".
(15) Comment: Cold filling method is used to fill hydrocarbon aerosols.
5 Attempt any THREE of the following : 12
(1) Briefly discuss the formulation, preparation and packaging of following preparations.
1. Hair Shampoo
2. Lipstick
(2) Describe various quality control tests for parenterals and explain sterility testing in detail.
(3) Write note on various type of glasses as described by USP and NF.
(4) Discuss the cGMP guidelines given for equipments used in pharmaceutical manufacturing.
6 Attempt any TWO of the following : 12
(1) Discuss all the sequential steps involved in the manufacturing of tablets and their importance. Write steps in tablet compression cycle.
(2) Explain soft gelatin capsule manufacturing by Rotary die process.
(3) What do you mean by Lyophillization ? Explain lyophillization in detail with schematic diagram.
SB-1172] 3 [ 600 ]
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| Earning: Approval pending. |
