Veer Narmad South Gujarat University 2011-4th Year B.Pharm SB-1175 PH- 405 Pharmacology - 3 a - Question Paper
SB-1175
Final Year B. Pharm. Examination March / April - 2011 PH - 405 : Pharmacology - III
(Pharmacology & Drug Bioevaluation)
Time : 3 Hours]
[Total Marks : 70
Instructions :
Seat No.:
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Fillup strictly the details of signs on your answer book.
Name of the Examination :
Final Y. B. Pharm.
Name of the Subject:
PH - 405 : Pharmacology - 3
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-Subject Code No.: |
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-Section No. (1,2,.....): 1&2 |
(2) This paper contains two sections.
Student's Signature
(3) Each section contains three questions.
(4) All three questions in each section are compulsory.
(5) Figures to the right indicate marks.
1 Discuss the role of following in the clinical conditions 15
mentioned : (any three)
(a) Glucocorticoids in asthma.
(b) Lithium in bipolar maniac depressive psychosis.
(c) Proton pump inhibitors (PPIs) in ulcer.
(d) Ethosuximide in epilepsy.
(e) Fluoxetine in depression.
(f) Gemfibrozil in antihyperlipidemia.
Discuss the detail pharmacology of the following : (any two) 10
(i) Morphine
(ii) Digitalis
(iii) Nitrates
(v) Warfarin.
Explain genetic polymorphism with five different 10
examples of variations in drug response.
OR
3 What is the difference between pharmacogenetics 10
and pharmacogenomics ? Discuss the role of gene therapy in various clinical conditions.
4 (a) Describe in detail, the five types of adverse drug 15
reactions (ADRs) with their specific characteristics with appropriate examples.
(b) Discuss the factors responsible for causing ADRs.
5 Enumerate and discuss the side effect profile of 10 any two of the following :
(i) Insulin
(ii) (3 -blockers
(iii) Diuretics
(iv) Non steroidal anti inflammatory drugs (NSAIDs).
6 Explain drug interactions at metabolic level with at 10 least five examples with their respective mechanism of actions and the final outcome of the reactions.
SB-1175] 2 [ 400 ]
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Attachment: |
| Earning: Approval pending. |
