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University of Pune 2010 M.Pharm Pharmacology Mpharmacy - Question Paper

Tuesday, 23 April 2013 06:55Web



Total No. of Questions : 8]    [Total No. of Pages : 2

P2H2S    [3757]-207 M. Pharmacy MOLECULAR PHARMACOLOGY (2008 Pattern) (M-III-4) (Semester - II)

Time: 3 Hours]    [Max. Marks: 80

Instructions to the candidates:

1)    Q.I and Q.5 are compulsory.

2)    Solve any two questions from the remaining in Section I and Section II.

3)    Figures to the right indicate full marks.

4)    Write answers for Section I and Section II in separate answer sheets.

SECTION - I

Q1 Discuss basic concepts of chronopharmacology and their implications on drug therapy.    [10]

Q2) Describe ion channel and their modulators for chloride channels. [15]

Q3) Enlist various endogenous bioactive molecules. Add a note on endothelium derived vascular substances.    [15]

Q4) Write a note on (Any two) :    [15]

a)    Serotonin receptors.

b)    Cyclic neucleotides.

c)    Transgenic mouse.

SECTION - II

Q5) Discuss in detail cellular cytotoxicity.    [10]

Q6) Describe pharmacology and therapeutic application of reactive oxygen intermediates.    [15]

07) What do you mean by adhesion therapy? Comment on vascular remodeling.

[15]

08) Write a note on (Any two) :    [15]

a)    Ion channels and their modulators.

b)    Opoid receptors.

c)    Human genome mapping.

[3757]-207    2







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