University of Pune 2010 B.Pharm PHARMACOLOGY – III (Including Clinical)(2004 ) - Question Paper

[3856] – 42
Fourth Year B.Pharmacy Examination, 2010
PHARMACOLOGY – III (Including Clinical)(2004 Course)
Time : three Hours Max. Marks : 80
Instructions :
1) ques. number one and five are compulsory. Out of the remaining attempt any two ques. from part I and two ques. from part II.
2) Answers to the 2 parts should be written in separate book.
3) Figures to the right indicate full marks.

part – I
1. Classify the drugs used for the treatment of myocardial ischemia. discuss in detail pharmacology of organic nitrates. 12

2. Classify antituberculor agents. discuss in detail chemotherapy of tuberculosis. Add a note on drugs used for mycobacterium avium complex. 14

3. Classify anticancer agents. Write in detail pharmacology of any 1 alkylating agent. 14

4. Write a note on any 2 : 14
A) Non-pharmacological therapy of hypertension.
B) Superinfections.
C) Epipodophyllotoxins.

part – II
5. discuss in detail kinds and phases of clinical trials. explain in detail design and interpretations of double blind placebo control clinical trials. 12

6. elaborate the limitations of bioassays ? discuss the design and detail procedure of bioassay of titanus antitoxin. 14

7.
A) discuss in detail local and systemic toxicities. 14
B) Add a detail note on factors influencing toxicity of drugs.

8. Write a note on any 2 : 14
A) Prevention and treatment of poisoning.
B) Adverse drug reactions.
C) Treatment of arsenic poisoning.

Earning:   Approval pending.