University of Pune 2010 B.Pharm 1.3 : PHARMACEUTICAL INORGANIC CHEMISTRY (2008 Pattern) - Question Paper

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First Year B.Pharmacy Examination, 2010
1.3 : PHARMACEUTICAL INORGANIC CHEMISTRY (2008 Pattern)
Time : three Hours Max. Marks : 80
Instructions :
1) All ques. are compulsory.
2) Answers to the 2 parts should be written in separate ans books.
3) Figures to the right indicate full marks.

part – I
1. What is radioactive decay ? explain the properties of  , and radiations. 10
OR
1. discuss the terms 'pharmacopoeia' and 'monograph'. Enlist various Pharmacopoeias and explain salient features of monograph. 10

2. Attempt any 5 of the subsequent : 15
a) discuss the limit for chloride for potassium permanganate as per IP.
b) Why the tube is packed with dried cotton wool impregnated with lead acetate solution while carrying out limit test for arsenic ?
c) discuss the terms hydrogen ion concentration, pH and pOH.
d) discuss the terms buffer action and buffer capacity.
e) explain the role of oxygen in biological system.
f) provide the properties, uses and method of assay of ammonia.
g) Write in brief about adsorbents.

3. Write notes on any 3 of the subsequent : 15
a) Water as pharmaceutical vehicle
b) explain role of buffers in pharmacy.
c) Storage conditions as detailed in I.P.
d) Raw materials as source of impurities in pharmaceuticals.
e) Methods of softening water.

part – II
4. How the acid base balance of the body is maintained ? 10
OR
4. explain the mechanism of action of topical protective agents with examples. discuss the properties, uses and method of assay of talc and zinc oxide.

5. Attempt any 5 of the subsequent : 15
a) discuss the term milliequivalent. compute the number of mEq of potassium chloride in 1 liter of a 0.48% w/v solution.
b) List the compounds of calcium and magnesium used as antacid.
c) discuss assay of ferrous sulphate, along with reactions.
d) explain mechanism of action of anti-caries agents.
e) define preparation and mechanism of action of antimony potassium tartarate.
f) describe antidotes and discuss their mechanism of action.
g) define with principle and reactions assay of ammonium chloride.

5. Write notes on any 3 of the subsequent : 15
a) Electrolyte combination therapy
b) Ideal properties of antacids
c) Antidotes
d) Physiological role of copper
e) Saline cathartics

Earning:   Approval pending.