University of Pune 2010 B.Pharm 2.6 : Pharmaceutical Biochemistry (Including Clinical Biochemistry)(2004 ) - Question Paper

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Second Year B.Pharmacy Examination, 2010
2.6 : PHARMACEUTICAL BIOCHEMISTRY (Including Clinical Biochemistry)(2004 Course)
Time : three Hours Max. Marks : 80
Instructions :
1) ques. one and five are compulsory. Out of the remaining attempt 2 ques. from part I and 2 ques. from part II.
2) Answers to the 2 parts should be written in separate books.
3) Neat diagrams should be drawn wherever necessary.
4) Black figures to the right indicate full marks.

part – I
1. a) describe enzyme inhibitor and discuss reversible and irreversible inhibition of
enzymes. 10

2.
a) define in detail structure of protein. 10
b) define structure of cell membrane with diagram. 5

3.
a) elaborate marker enzymes ? provide applications of marker enzymes. 8
b) discuss structure of starch and glycogen. 7

4. Write short notes on the subsequent (any three) : 15
a) Color reactions of amino acids
b) Factors affecting enzyme activity
c) Phospholipids
d) Transport across cell membrane.

part – II
5. discuss various mechanism to maintain physiological acid base balance in body. 10

6.
a) define Glycolysis along with its regulatory enzymes. 10
b) define absorption, transport and storage of Iron in body. 5

7.
a) discuss DNA replication. 8
b) define synthesis of vitamin – D in body. 7

8. Write short notes on the subsequent (any three) : 15
a) Clearance tests as kidney function tests
b) Structure of t RNA
c) ß oxidation of fatty acids
d) Transamination.

Earning:   Approval pending.