University of Pune 2010 B.Pharm 2.7 : Pharmacology – I(Including Pathophysiology)(2004 ) - Question Paper

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Second Year B.Pharmacy Examination, 2010
2.7 : Pharmacology – I(Including Pathophysiology)(2004 Course)
Time : three Hours Total Marks : 80
Instructions:
1) Q. one and five are compulsory. Solve any 2 ques. of the remaining from part A and part B.
2) Figures to teh right indicate full marks.
3) ans to the part A and B shall be written on separate ans sheet.

part – A
1. describe drug distribution. define role of plasma proteins in drug distribution. 10

2.
a) discuss durg toxicity in man with suitable examples. 8
b) describe antiplatelet agents, write pharmacology of any 1 drug. 7

3.
a) explain drug treatemnt in menstruation. 8
b) Exsplain molecular and biochemical mechansim of drug action. 7

4. Write a note on (any three) : 15
a) Devlopment of new drug
b) Sources of drugs
c) HMG-Co- A reductase inhibitors
d) Drug-refceptor interactions. 

part – B
5. describe hepatitis, classify it and explain pathophysicology of hepatitis-B. 10

6.
a) Classify depression, enlist its clinical manifestation and explain management with suitable examples. 8
b) discuss phathophysiology of diabetes mellitus. 7

7.
a) describe pain and add a note on pathophysiology of pain. 8
b) define causes, progress and management of congestive cardic failure. 7

8.
a) Enlist different kinds of pneumonia. Add a note on any 1 kind. 8
b) explain stages of cancer with suitable examples. 7

Earning:   Approval pending.