University of Pune 2010 B.Pharm Pharmaceutical Chemistry – I (2004 )(Inorganic) - Question Paper

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First Year B.Pharmacy Examination, 2010
Pharmaceutical Chemistry – I (2004 Course)(Inorganic)
Time : three Hours Max. Marks : 80
Instructions :
1) ques. No. one from part I and ques. No. five from part II are compulsory.
2) Out of remaining ques. solve two ques. from part I and two ques. from part II.
3) Answers to the 2 parts should be written in separate books.
4) Figure to the right indicate full marks.

part – I
1.
a) explain the role of major extracellular and intracellular electrolytes. 8
b) Write principle involved in limit test for lead. 2

2.
a) discuss role of fluoride and phosphate in tooth decay. 5
b) describe hardness of water and state the methods to remove hardness of water. 5
c) What is radiopaque contrast media ? discuss barium sulphate as radiopaque contrast media. 5

3.
a) discuss the role of Iron in body. 5
b) Enlist sources of impurities in pharmaceutical substances and discuss their effect on pharmaceutical substances. 5
c) define limit test for Iron. 5

4.
a) describe antidote, explain various antidotes with their mechanism of action. 5
b) describe monograph. what are contents of monograph. 5
c) explain in brief applications of radiopharmaceuticals. 5[3856] – 13 

part – II
5.
a) elaborate protective and adsorbents ? define 2 official compounds used as protective. 5
b) describe the terms buffer, emetics, cathartics, antacid and expectorant. 5

6.
a) Classify topical agents on the basis of their actions with example. 5
b) explain in brief antioxidants. 5
c) describe and classify inorganic Gastrointestinal agents. 5

7. Write short notes on (any five) : 15
a) Astringents
b) Protectives
c) Assay of KI
d) Assay of NH4
e) Combination Antacids
f) Preservatives.

8.
a) explain in brief antimicrobial agents. 5
b) explain the source, physiological importance and compounds of Iodine. 5
c) discuss the role of oxygen, carbon dioxide in human body. 5

Earning:   Approval pending.