University of Pune 2010 B.Pharm 2.1 : Pharmaceutics – II (Physical Pharmacy) (2004 ) - Question Paper

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Second Year B.Pharm. Examination, 2010
2.1 : Pharmaceutics – II (Physical Pharmacy) (2004 Course)
Time : three Hours Max. Marks : 80
Instructions :1) ques. Nos. one and five are compulsory. Out of the remaining attempt two ques. from part I and two ques. from part II.
2) Answers to the 2 parts should be written in separate books.
3) Neat diagrams must be drawn wherever necessary.

part – I
1. elaborate colligative properties of nonelectrolytes ? How these can be used to determine molecular weight of the substance ? discuss in detail. 10

2. discuss in detail polymorphism. provide its application to pharmacy. 15

3.
A) discuss in detail solubility of gases in liquids. 7
B) What is partition coefficient ? provide its application in pharmacy. 8

4. Write short note on (any 3) : 15
1) Conductometric titrations.
2) different methods of crystal analysis.
3) 1 component system.
4) 1st legal regulations of Thermodynamics.

part – II
5. describe surface tension. discuss various methods of determination of surface tension. 10

6. discuss what is order of reaction. explain different methods of determination of order of reaction. 15

7. provide importance of particle size determination in pharmacy. discuss different methods to determine particle size. 15

8. Write short note on (any 3) : 15
1) Adsorption isotherm.
2) Thixotrophy.
3) Derived properties of powders.
4) HLB (Hydrophilic Lipophilic Balance).

Earning:   Approval pending.