Integral University 2009 M.Tech Biotechnology Immunotechnology - exam paper
No of Printed Pages - 2 MTBT-302(A)
3 Roll No.
d
THIRD SEMESTER EXAMINATION. 2008-09 1MMUNOTECHNOLOGY
Note: (I) Attempt any FIVE questions.
(II) Marks are indicated against each question.
1. What do you understand by passive immunotherapy? With examples illustrate that how it \s helpful in treating immunodeficiencies? 20
2. (a) Write down the objective of using each of following items In hybridoma technology:
(I) Polyethylenegtycot;
(III) HAT medium 10 (b) What are chimeric monoclonal antibodies and Indicate how the
monoclonal antibodies against lnterieukin-2 receptor are used clinically? 10
3. Elucidate the mechanism of entry of HIV Into a host cell with the help of a well labeled diagram and Indicate the distinction of the co-receptor on a T cell and a macrophage. 20
3
3 4 (a) Describe the role of antibodies In Immunity against tumors 15
(b) Mention the two Important immunotherapeutic measures (or malignant tumors. 5
P.T.O.
MTBT-302(A)
5. (a) Describe In detail the effector mechanism of allograft rejection with
special reference to kidney transplantation 15
(b) Immunosuppression to prevent allograft rejection 5
6. Give a detailed account of lnterteukin-12 stating Its source of secretion, biological action and cUnlcal use 20
7. Illustrate the various uses of recombinant DNA technology in cJinical diagnosis and vaccine 20
OR
Wnte short notes on any Two of the following: 10 x 2 = 20
(a) Interferons and therapeutic potential
(b) Peptide therapy
(c) Polyclonal antibodies
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| Earning: Approval pending. |
