Indian Institute of Technology Roorkee (IIT-R) 2009-2nd Year B.Tech Biotechnology Bioinformatics, - Question Paper
BT 217 BIOINFORMATICS, AUTUMON SEMESTER (2009-2010)
B.Tech II Year, Biotechnology
Final examination
Summary:
This ques. paper covers the basic aspects of bioinformatics like homology, modelling, basic programs such as PYMOL and COOT. It also contains issues on few basic matrices.
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B.Tach-11 (BIOTFCHN<)!.<H i V)
Final lixnm.
Kmc: /J1 questions carry equal ivmrks,
. 1. Outline the role I iioin formal ics couki *n stiuciuiv* Med \\uty asmsminsL.
Z Wiiai is BLAS T ami why il is used? IVfine jvur-wis* MMvl multiple icaiJtCTi alignments, Del me F.-XiUuc?
3 ixniain the CU JSIAI AV and FSPRU'F. Discuss the utfYimlu ul usmLi PSJ and Pill HI,AST,
V.hai are PKOFILK and PA I'l'l'KN? <Li\o cvimptes*
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5 .Sw-tim: with a protein sequence* man\ diftcrvnt ixpcot iufvMUwUioii nr imuiined from hioinlormatics a'souivvs available on UiO wotld uti4l web. Describe these resources* atni iheir applications in pioieih roararifrnzatjon and analysis,
t- 1 r ptw-Uble to predict (ho 30 stmcturc aifci function of tt pttloin iror- fit nucleotide sequence? llo\0
,/T. I/dme urihoJogs and paralojjs in terms of cxoUittotuUA voiwepls, Gnvr rxampleb.
vt. Ivplaiu (he Active silo X fold ai>d <ic$crtbe about (*OOI mul Pi'ftlOL molecular visualization software, IVscribo tour uppliiHilions u/iwnr wfiwdjv'j.
'"L' v/uaI arc main websites lor protein sc\v*kiar\ stiucUuo pl'vdUliuos im vvita? we ihe oiiiptifs lW>m ihcnv? F\pkun the ditlotvmv Mwwii jMVuuivjg inout'Jjjii. uikI threading
11 Wm art the methods lor moUvuUr Avkin? tVscril o tin* docking -juifiM-jffit input requirement and ohat arc the outputs tVom II I Ui lluve #dfw*fr:ri> name and desctibe one of them*
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