Tamil Nadu Dr MGR Medical University 2009 M.Pharm PHARMACEUTICAL BIOTECHNOLOGY II – PHARMACEUTICAL ASPECTS OF MICROBIAL AND CELLULAR BIOLOGY - - Question Paper

MARCH -2009
[KU 331] Sub. Code: 2867
M.PHARM. DEGREE exam
(Regulations 2006)
(Candidates admitted from 2006-2007 onwards)
FIRST YEAR
Branch VI – PHARMACEUTICAL BIOTECHNOLOGY
Paper II – PHARMACEUTICAL ASPECTS OF MICROBIAL AND CELLULAR BIOLOGY
Q.P. Code : 262867
Time : 3 hours Maximum : 100 marks
ans All ques.
I. Essay ques. : (3 X 20 = 60)
1. discuss the basic chemical structure of DNA. How is it replicated and what is its role in protein synthesis? Detail the synthesis of protein.
2. discuss different methods of how pure microbial cultures are isolated and maintained.
3. a) define the replication of viruses.
b) What is Lysogeny? define the mechanism of lysogeny.
II. Write Short Notes : (8 X five = 40)
1. Basic aspects of cell regulation.
2. Secondary metabolites and its applications.
3. Bacterial growth curve.
4. Auto immune diseases.
5. Mechanism of microbial pathogenicity.
6. Mutagenesis in strain improvement.
7. Applications of animal cell culture.
8. Continuous and synchronous culture.
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Earning:   Approval pending.