Tamil Nadu Dr MGR Medical University 2009 B.Pharm I – PHARMACEUTICAL INORGANIC CHEMISTRY Q.PCode : 564226 - - Question Paper

FEBRUARY – 2009
[KU 735] Sub. Code: 4226
FIRST B.PHARM. DEGREE exam
(Regulations 2004)
(Candidates admitted from 2004-05 onwards)
Paper I – PHARMACEUTICAL INORGANIC CHEMISTRY
Q.P. Code : 564226
Time : 3 hours Maximum : 90 marks
I. Essay ques. : (2 X 20 = 40)
ans any 2 ques..
1. a) define the sources of impurities in pharmaceutical substances. discuss
the principle involved in the limit test for sulphate with eqvation. (13)
b) Write the clinical applications of I ¹³¹ cobalt 58 and barium sulphate. (7)
2. a) describe antacid? Classify antacids and advantages of combination
therapy. (12)
b) Write the properties and assay, uses of magnesium trisilicate: (8)
3. a) discuss the theories of co-ordination compounds?. Write the applications
in pharmacy for the subsequent compounds. i) Dimercapral ii) EDTA. (14)
b) discuss the Indian pharmacopiea and monograph with an examples. (6)
II. Write Short Notes : ans any 8 ques.. (8X five = 40)
1. What is radioactivity? How to measure Radioactivity and discuss any 1 method.
2. Write short note on limit test for Arsenic?
3. Short notes on: a) Magnesium hydroxide. b) Activated charcoal
4. a) Write a note on protectives provide 2 examples.
b) Write short note on Calamine.
5. a) Write the principle involved in the assay of boric acid.
b) discuss the method of preparation of lithium aluminium hydride.
6. elaborate the medicinal gases? How to prepare and assay of carbondioxide?
7. a) discuss the physiological role of trace ions.
b) Short note on Ion-dextron injection.
8. provide the preparation and uses of any 2 antioxidants.
9. Write short note on anticaries agents.
10. Expectorants.
III. Short Answers: ans any 5 ques.. (5X2 = 10)
1. describe sedatives with examples.
2. Complete the subsequent reactions:
a) Na2CO3 + H2O+ 2SO2 ? b) NaOH + HCL ?
3. provide the preparation and uses of ferrous sulphate.
4. Write the physiological role of a) Sodium b) Magnesium.
5. describe the terms: a) Antacids. b) antimicrobials
6. Write the pharmaceutical application of
a) Cyancobalamine (Co58) b) Sodium phosphate (P³²).
7. Write the molecular formula of the following:
a) Lithium aluminium hydroxide b) Thionyl chloride.

Earning:   Approval pending.