Tamil Nadu Dr MGR Medical University 2009 B.Pharm II %EF%BF%BD%EF%BF%BD%EF%BF%BD%EF%BF%BD%EF%BF%BD%EF%BF%BD%EF%BF%BD%EF%BF%BD%EF%BF%BD PHARMACEUTICAL BIOTECHNOLOGY Q.PCode %3A 564222 - - Question Paper

FEBRUARY – 2009
[KU 731] Sub. Code: 4222
FOURTH B.PHARM. DEGREE exam
(ReRevised Regulations)Candidates Admitted upto 2003-04
Paper II – PHARMACEUTICAL BIOTECHNOLOGY
Q.P. Code : 564222
Time : 3 hours Maximum : 90 marks
I. Essay ques. : (2 X 20 = 40)
ans any 2 ques..
1. a) describe immunity and distinguish active with passive immunity.
b) discuss the design and construction of fermentor.
2. define in detail the microbiological assay of vitamins.
3. discuss the production and valuation of BCG vaccine.
II. Write Short Notes : (8X five = 40)
ans any 8 ques..
1. Briefly discuss continuous culture.
2. Differentiate ranging from toxins and toxoids with examples.
3. Write a short note on bacterial growth curve.
4. Write briefly on preparation of injection of penicillin.
5. provide a brief account of containerization vaccines.
6. Write the applications of monoclonal antibodies.
7. Briefly discuss amylase production.
8. Write in detail about autoimmune disorders.
9. Write a short note with application of immunoglobulin.
10. Non absorbable sutures.
III. Short Answers: (5X2 = 10)
ans any 5 ques..
1. discuss any 4 factors that affect disinfectant activity.
2. provide 2 examples every of disinfectants and preservatives used in
pharmaceutical preparations.
3. Write stability studies defined for official vaccines.
4. describe the terms bioreactor and biosensor.
5. Write the procedure for the western blotting technique.
6. Write the application of biosensors.
7. Illustrate multiple streaking technique.

Earning:   Approval pending.