Tamil Nadu Dr MGR Medical University 2009 B.Pharm I – PHARMACEUTICAL BIOTECHNOLOGY Q.PCode : 564242 - - Question Paper

FEBRUARY – 2009
[KU 751] Sub. Code: 4242
FOURTH B.PHARM. DEGREE exam
(Regulations 2004)Candidates Admitted from 2004-05
Paper I – PHARMACEUTICAL BIOTECHNOLOGY
Q.P. Code : 564242
Time : 3 hours Maximum : 90 marks
I. Essay ques. : (2 X 20 = 40)
ans any 2 ques..
1. Write in detail about recombinant DNA technology. Write about the
production of Insulin by recombinant DNA technology. (20)
2. a) describe and classify sterilization. (5)
b) Write in detail about the principle, operation and design of industrial
horizontal jacketed autoclave. (15)
3. a). Write in detail about the ultra structure of bacteria. (15)
b). Bacterial reproduction and synchronous growth. (5)
II. Write Short Notes : (8X five = 40)
ans any 8 ques..
1. Rideal Walker test.
2. Microbiological assay of antibiotics.
3. ELISA.
4. Production of Industrial alcohol.
5. Immobilization of Enzymes.
6. Methods for cultivation of Virus.
7. Gene transfer by Conjugation.
8. Cholera vaccine.
9. Composition of culture media for animal cell culture.
10. Monoclonal antibodies.
III. Short Answers: (5X2 = 10)
ans any 5 ques..
1. Write in brief about pasteurization.
2. Differentiate ranging from active immunity and passive immunity.
3. describe Haptens with suitable example.
4. describe the terms: a) Bacteriostatic b) Bactericidal c) Disinfectant
d) Antiseptic.
5. Write in short about the applications of animal cell tissue culture.
6. Write any 2 methods for counting Viable bacteria.
7. Differentiate ranging from yeast and moulds.

Earning:   Approval pending.