Tamil Nadu Dr MGR Medical University 2009 B.Pharm VI – MEDICINAL CHEMISTRY – II Q.PCode : 564247 - - Question Paper

FEBRUARY – 2009
[KU 756) Sub. Code: 4247
FOURTH B.PHARM. DEGREE exam
(Regulations 2004)Candidates Admitted from 2004-05
Paper VI – MEDICINAL CHEMISTRY – II
Q.P. Code : 564247
Time : 3 hours Maximum : 90 marks
I. Essay ques. : (2 X 20 = 40)
ans any 2 ques..
1. provide brief introduction to computer aided drugs designing (CADD)
and molecular modelling with suitable examples.
2. elaborate synthetic anti bacterial agents? define them in detail, the
methods of preparation, SAR , toxicity and uses.
3. define in detail the classification, mechanism of action, toxicity and
uses of anti cancerous drugs.
II. Write Short Notes : (8X five = 40)
ans any 8 ques..
1. Synthetic hypoglycemic agents.
2. Antihelmenthtics.
3. Mineralocorticoides.
4. Anti-arrythmic drugs.
5. Unclassified antibiotics.
6. Antiscabies agents.
7. Classification and uses of antiprotozoal drugs.
8. SAR of antimalarials.
9. Mercaptopurines.
10. Androgens.
III. Short Answers: (5X2 = 10)
ans any 5 ques..
1. Classification of Sulpha drugs.
2. Congored.
3. Clofibrate.
4. Eugenol.
5. Nalidixic acid.
6. Ketoconazol

Earning:   Approval pending.