Saurastra University 2006 M.B.B.S Biochemistry - - II - Question Paper
First Year M.B.B.S. Examination February - 2006 Biochemistry - Paper - II
Time : 3 Hours] [Total Marks : 50
Instructions : (1) Each section should be answered in separate
answer books.
(2) Answers should be brief and to the point. SECTION -1
1 State true or false with justification on : (any six) 6
(a) In anaerobic glycolysis pyruvate is produced.
(b) Rapaport leubering cycle is beneficial to RBC.
(c) Fat can not be metabolised in the absence of carbohydrates.
(d) Bile salts are not required for fat digestion and absorption.
(e) In alkaptonurea, urine turns black on exposure to air.
(f) Salvage pathway is more economical than de - nove synthesis.
(g) Carnitine is essential for oxidation of all types of fatty acids.
(h) In ETS P : O ratio is always 3.
2 Discuss the following : 10
(a) Glycogen storage diseases.
(b) Disorders of aromatic amino acid metabolism.
3 Write short notes on : (any three) 9
(a) Diabetes mellitus
(b) Glycolysis
(c) GTT
(d) Urea cycle
(e) Lipids : digestion, absorption and transport
4 Give your comments with justification on : (any six) 6
(a) Citric acid cycle does not operate in RBC.
(b) Hyperuricemia is seen in Von Gierke's disease.
(c) Uncontrolled diabetes will lead to metabolic acidosis.
(d) L CAT deficiency leads to atherosclerosis
(e) High HDL - cholesterol level is a welcome sign.
(f) Iron defeciency anemia can be produced in vitamin C deficiency.
(g) Calcuium deficiency leads to osteomalacia.
(h) Aspirin is used as an anti-inflamatory drug.
5 Discuss any two : 10
(a) Heme biosynthesis and regulation.
(b) Metabolic reactions of glycine.
(c) Electron transport system.
6 Write short notes on : (any three) 9
(a) pH and its regulation
(b) Ca++ metabolism
(c) PEM
(d) Conjugation
(e) Ketogenesis.
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