Saurastra University 2006 B.Pharm Pharmaceutical Technology - Question Paper

Fourth Year B. Pharm. exam
March / April – 2006
Pharmaceutical Technology
Time : three Hours] [Total Marks : 80
Instructions: (1) Attempt four (four) ques. from every part.
(2) Write every part in separate ans book and
tie it separately.
(3) Maximum marks are 80 (eighty) only and all
ques. carry equal marks.
part - I
1 Write comments on any 5 of the followings :
(a) Production of hard gelatin capsules should be carried
out at controlled humidity.
(b) All kinds of tables require disintegrating agents.
(c) Sugar coating increases the weight of tablets.
(d) Capsules do not require disintegration test.
(e) Pyrogens can be removed by heating at 180
o
C for 60
seconds.
(f) Water attack test is performed on ground sized glass
particles.
(g) Bioavailability of ophthalmic ointments is greater than
ophthalmic solutions.
2 (a) explain the factors affecting locational aspects of
pharmaceutical plants.
(b) explain the valuation tests for suspensions OR parenteral
products.
3 Attempt any 2 of the followings :
(a) Classify different semisolid bases and explain their properties.
(b) Write a short note on Radio Pharmaceuticals.
(c) Write a short note on Propellants in brief.
4 (a) explain the properties of ideal suppository base.
(b) explain the compression cycle of rotary tablet machine with
diagram.
SA-7666] two [ 100 ]
5 Attempt any 2 of the followings :
(a) explain the formulation ingredients of ophthalmic products.
(b) explain valuation methods of ophthalmic preparations.
(c) Write a note on ‘Occusert’.
part - II
6 Write comments on any 5 of the followings:
(a) Blends of propellants are used in aerosol products.
(b) All kinds of tablets do not require sterility.
(c) Directly compressible diluents are more preferred for
less compactable drugs.
(d) The fluidized bed systems are used for drying the
granules only
(e) Polypropylene is widely is used as a parenteral container.
(f) Parenteral emulsions contain oil droplets of one to 5
microns in size.
(g) Elixirs and spirits are synonymous liquid products.
7 (a) explain the advantages and disadvantages of hard gelatin
capsules.
(b) discuss the methods of preparation of soft gelatin capsules.
8 (a) What is micro-encapsulation? explain any 1 method of
micro-encapsulation.
(b) Write a note on dentifrices OR Shampoos.
9 Attempt any 2 of the followings :
(a) explain the issues of tablet manufacturing with their
remedies.
(b) Write a note on penetration enhancers.
(c) Write a note on effervescent granules.
10 Attempt any 2 of the followings :
(a) explain the layout of an aesptic area.
(b) explain the advantages and disadvantages of aerosol products.
(c) explain the packaging methods of aerosol products.
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Earning:   Approval pending.