Punjab Technical University 2010-4th Sem B.Sc BioInformatics M.Sc(BI) (th) PROTEOMICS - Question Paper

[Total No. of Pages : 02

Roll No........................

Total No. of Questions : 13]

[2037]

M.Sc. (BI) (Semester - 4^th) PROTEOMICS (M.Sc. (BI) - 404)

Maximum Marks : 75

Instruction to Candidates:

1)    Section-A is compulsory.

2)    Attempt any Nine questions from Section-B.

Section - A

(15 x 2 = 30)

a)    Global alignment

b)    PAM matrix

c)    Homology

d)    Dendrogram

e)    T-coffee

f)    Motif

g)    Tertiary structure

h)    Treading

i)    CATH

j)    Ramachandran Plot

k)    Rasmol

l)    Gap penalty

m)    Dot plot

n)    Geometric hashing

o) PSI-BLAST

(9 x 5 = 45)

Q2) Discuss in short the importance of protein multiple sequence alignment. Q3) Write a short note on CLUSTALW.

Q4) Write in brief various steps involved in Homology modelling.

Q5) Discuss in detail BLAST output.

Q6) Write a note on Deep view.

Q7) Write a note on Ab-initio protein structural prediction.

Q8) List the differences between BLAST and Fasta.

Q9) Write a short note on Substitution matrices.

Q10) Discuss in detail dynamic programming.

Q11) Discuss in short any three programmes related with automatic structural classification of proteins.

Q12) Discuss in detail flexible matching.

Q13) Write a short note on protein folding.

nnn

D-8    2

Attachment: punjab-technical-university-2010-b-sc-bioinformatics-23485-1.pdf

Earning:   Approval pending.