Jaypee Institute of Information Technology (JIIT) 2008 B.E Test 3 : Drug Discovery and Production Technology - Question Paper

Note: Attempt all the questions. 1. Define followings terms

JAYPEE UNIVERSITY OF INFORMATION TECHNOLOGY

WAKNAGHAT

TEST- 3 (November. 2008) a TECH. (VSF.Mf.STFR, BT & BTDD)

a)    Biouansfonrwtion

b)    Negative antagonist

c)    Aniimetabohte

d)    Proteoraics

e)    OSAR

2.    Justify the statements    (5 Marks)

a)    Acidic drugs are best absorbed in stomach.

b)    Benzyl penicillin is not given orally.

c)    Drug Discovery is a highly complcx and multidisciplinary process.

d)    Microorganisms have been invaluable for discovering lead compounds and drugs.

c) Rate of absorption is faster in inua-muscular route than subcutaneous route

3.    Explain in detail the Drug Discovery from Natural sources Abo. explain the advantages and disadvantages of Natural product based Drug Discover) process?

(5 Marks)

4.    Write a note on the followings.    (5 Marks)

a)    Prod rugs

b)    Soft and Hard drugs

5.    a) Asa Head of Drug Development, Explain your approaches for developing new

drug molecule. Explain the mjor hurdles in you drug development programs, b) Explain the different factors affecting drug absorption and distribution.

<3 2 5 Marks)

Attachment: jaypee-institute-of-information-technology--jiit--2008-b-e-21249-1.jpg

Earning:   Approval pending.