Uttar Pradesh Technical University (UPTU) 2007 B.Pharm Pharmaceutical Chemistry-II(Organic Chemistry-I)(Special Carryover) - Question Paper

Printed Pages : 3    PHAR- 122

(Following Paper ID and Roll No. to be filled in your Answer Book)

Roll No.

B. Pharm.

(SEM. II) EXAMINATION, 2006-07 PHARMACEUTICAL CHEMISTRY - II (ORGANIC CHEMISTRY - I)

(SPECIAL CARRYOVER EXAMINATION)

Time : 3 Hours]    [Total Marks : 80

Notes : Answer all the questions. All questions carry equal marks.

1 (a) Give IUPAC name of : (any four)

CH_sCOCH₂ CH₂ CO CH₂ CH = CH₂;

Br OCH₃

CH_S - CH- CH - CH₂ - CH- CH-CH = CH₂

nh₂

1

(b) Write about different quantum numbers.

OR

(b)    Define electrovalent, covalent and co-ordinate bonds.

(c)    Give the chemical structure of :

Methyl - 2 - bromo - 4 - cyano -

3    -hydroxypentanoate;

5 - Bromo - 4 - ethoxy - cyclopent - 2 en - 1 - one;

2 - Chloro - 3 - bromo - 4, 4 - dimethyl pentanal;

4    - Methyl - hept - 2en-5yn- 1 - 01.

(d)    Define resonance with suitable examples.

(a) Write about structural isomerism with suitable examples.

OR

(a)    Define enantiomers. How will resolve the enantiomers from a racemic mixture ? Explain with suitable examples.

(b)    Give the different conditions required for conformational analysis. Write about R and S configuration.

3 Answer the following :

(a)    Free radical substitution reaction

(b)    Diels-Alder reaction

(c)    Give the important reactions of alkyl halides

(d)    Specific reactions of acetylene;

OR

(d) Electrophilic addition reactions in propene.

4    (a) Explain, why are chlorine deactivating but ortho

and para orienting group which N0₂ deactivating but meta orienting.

OR

(a)    Write about Friedel Craft acylation and Friedel Craft alkylation reactions.

(b)    Give the chemical properties of phenol.

5    (a) Why are aldehydes and ketones undergo nucleophilic

addition reactions ? Explain. Give the reactions of acetaldehyde with NH₂OH HCl; NaHS0₃; HCHO

and NaOH ; AgfNHg)* = OH

OR

(a)    Write about Reformatsky reaction, Knovenegal reaction and Benzoin condensation with mechanism (any two)

(b)    What is Grignard reagent ? Discuss the synthetic importance of Grignard reagent. How will you convert ethanoic acid into ethanoyl chloride, ethanamide; Ethylethanoate; and ethanoic anhydride.

Z-5068]    3    [ 1710 ]

Attachment: uttar-pradesh-technical-university--uptu--2007-b-pharm-20206-1.pdf

Earning:   Approval pending.