Uttar Pradesh Technical University (UPTU) 2010 B.Pharm Pharmaceutical Technology-II - Question Paper

B. Pharm (UPTU)
Sixth Semester exam (Year 2009-2010)
Pharmaceutical Technology-II

Time: three Hours Total Marks: 80

Note: 1) Attempt All ques..
2) All ques. carry Equal marks.

1) Answer any 4 questions: (4×4=16)
a) Explain any 2 methods used for "Production" of hard gelatin capsules cells.
b) Briefly discuss the process of microencapsulation by emulsion technique.
c) What is the application of minim/gm and base adsorption in case of soft gelatin capsules?
d) What are reasons for preference of solid dosage forms, i.e., capsules over other dosage forms? provide the kinds of microcapsules.
e) Give procedure for valuation of microcapsules.

2) Attempt any 4 questions: (4×4=16)
a) What are the various types of coated tables? discuss the advantages of every 1 of them.
b) Explain various types of granulation techniques used in tablet manufacturing.
c) What are the in-process and finished product quality control checks used while tablet manufacturing?
d) What will be the effect of variation of various formulation variables used in coating of tablets?
e) Explain any 1 Industrial method used in coating of tablets.

3) Attempt any 2 questions: (2×8=16)
a) Which physiological parameters should be considered while formulation of Nasal products?
b) Write brief note on (any Four):
i) Liposomes
ii) Microspheres
iii) Nanoparticles
iv) Resealed erythrocytes
v) Ocusert
c) What are the various mathematical models used for valuation of sustained and controlled release dosage forms?

4) Attempt any 2 questions: (2×8=16)
a) What are different preformulation tests done before designing a parentral product?
b) Explain a large scale manufacturing method for parentral product. Also provide the equipments used during every step of manufacturing.
c) Enlist and discuss the valuation methods used for sterile parentral products.

5) Attempt any 2 questions: (2×8=16)
a) Write short notes on absorbable and non-absorbable sutures.
b) What are factors that influence option of containers? Also enlist in detail the official requirements for containers.
c) How the components used for packaging evaluated with respect to their stability and usage?

Earning:   Approval pending.