Uttar Pradesh Technical University (UPTU) 2010 B.Pharm Pharmacology-II - Question Paper

B. Pharm (UPTU)
Sixth Semester exam (Year 2009-2010)
Pharmacology-II

Time: three Hours Total Marks: 80

Note: 1) Attempt All ques..
2) All ques. carry Equal marks.

1) Answer any 4 of the following: (4×4=16)
a) Classify anti-hypertensive drugs with suitable examples.
b) Discuss mechanism of action and adverse effect of Digitalis.
c) Give mechanism of action of any 2 drugs:
i) Nifidipine
ii) Propenolol
iii) Isoserbide dinitrate
d) Discuss adverse effect and interaction of methyldopa and clonidine.
e) Write short note on therapy of shock.

2) Answer any 4 of the following: (4×4=16)
a) Give adjuvant of Hematinics.
b) Classify various kind of drugs used to restore homeostasis.
c) Discuss pharmacological uses of fibrolytics.
d) Classify anti-platel drugs and discuss the mechanism of action of Aspirin.
e) Give mechanism of action of subsequent drugs:
i) Lovasttin
ii) Colestipol
iii) Nicotinic acid
iv) Fibric acid derivative

3) Answer any 4 of the following: (4×4=16)
a) Compare opoid and non-opoid antitussives.
b) Give classification of anti-asthmatic drugs.
c) Discuss mechanism of mast cell stabilizers.
d) Give pharmacological action of theophylline.
e) Write short note on expectorants.

4) Answer any 2 of the following: (2×8=16)
a) Describe synthesis, storage, receptors and mechanism of release of Histamine.
b) Give effects of prostaglandins and leukotrienes on CVS and kidney.
c) Write brief note on angiotensin and bradykinins.

5) Answer any 2 of the following: (2×8=16)
a) Discuss mechanism of action and pharmacological action of Pentoprazole.
b) Classify anti-emetics with suitable example. provide mechanism of chlorpromazine.
c) Write a note on treatment of diarrhea.

Earning:   Approval pending.