Uttar Pradesh Technical University (UPTU) 2009 B.Pharm Pharmaceutical Analysis-I - Question Paper

B. Pharm (UPTU)
First Semester Theory Examination, 2009-10
Pharmaceutical Analysis-I

Time: three Hours Total Marks: 80

Note: All parts are Compulsory.
Section-A

Attempt all the Questions: (1×16=16)
1) A red benzenoid form of methyl orange exists in the alkaline medium. (T/F)
2) Normality of oxalic acid is
a) Molarity/2
b) Molarity × 2
c) Both (a) and (b)
d) None of these.
3) Ionic product of water (Kw) is
a) Ka * Kb
b) Ka/Kb
c) Ka – Kb
d) Ka + Kb
4) Two gram of sodium hydroxide is dissolved in 1 litre of solvent to provide a solution of
a) 1N
b) 0.05N
c) 0.2N
d) 1/10N
5) Dissociation constant of a weak acid and its conjugate base are complementary. (T/F)
6) Indicators are ______ acid and bases.
7) Potassium iodide is more soluble in water than iodine. (T/F)
8) Reproducibility of the measurement is called accuracy. (T/F)
9) The H+ and OH– ion concentrations in pure water are equal at 25°C. (T/F)
10) Acid is an electron-pair acceptor according to
a) Bronsted-Lowry
b) Arrhenius
c) Lewis
d) None of these.
11) Solution of described concentration in titrimetric analysis is called ______.
12) Organic solvents do not affect the solubility of inorganic precipitates. (T/F)
13) Adsorption indicators are used in the ______ method.
14) ______ is used as an indicator for the determination of CI–/ Br– by Mohr's method.
15) The magnitude of random fault can be determined. (T/F)
16) The significant figure for 0.0029kg of sodium chloride would be
a) 2
b) 3
c) 4
d) 0

Section-B

Attempt any 6 of the subsequent questions: (4×6=24)
1) Write down in brief about applications of quantitative analysis in pharmaceutical field.
2) Give a short note on the dissociation of weak electrolyte with suitable examples.
3) Write a short note on the oxidation-reduction indicators.
4) What are the different factors which affect solubility of the precipitates?
5) Describe the Volhard's method taking the example of any pharmaceutical substance.
6) Define Titrant, titrand, self indicator and end point.
7) Describe the common ion effect with suitable examples.
8) How do buffers maintain the pH of solutions?

Section-C

Attempt any 4 ques. of equal marks: (4×10=40)
1) What is the role of neutralization indicators in determining the end point in acid-base titrations? provide a short note on neutralization curves.
2) Write short notes on:
a) Primary standard
b) Displacement titrations
c) Washing of the precipitate
d) Henderson-Hasselbach formula.
3) Explain in detail about Volhard's and Fajan's methods of precipitation titrations with suitable examples.
4) Define the term gravimetry. elaborate the different steps involved in the gravimetric analysis for the separation of precipitate?
5) Write down the theory of redox titrations. explain the oxidation-reduction curves with suitable examples.

Earning:   Approval pending.