Uttar Pradesh Technical University (UPTU) 2009 B.Pharm Pharmaceutical Chemistry-I (Inorganic Pharm Chem.) - Question Paper

B. Pharm (UPTU)
First Semester Theory Examination, 2009-10
Pharmaceutical Chemistry-I (Inorganic Pharm Chem.)

Time: three Hours Total Marks: 80

Note: Attempt All parts.
Section-A

1) Attempt all of the following: (1×16=16)
i) The formula for thioglycollic acid is
a) HS-CH2-COOH
b) HO-CH2-COOH
c) H2N-CH2-COOH
d) None of these.
ii) The subsequent is Not a source of impurity in pharmaceutical substances
a) Glass
b) Water
c) Nitrogen
d) Oxygen.
iii) The limit test of lead as per I.P. is done with the reagent _______.
iv) The main side-effect of Magnesium containing antacids is ______.
v) Sodium is an extra-cellular cation. (True/False)
vi) Light Magnesium Oxide is so called because it is capable of emitting light. (True/False)
vii) The equipment used for measurement of radioactivity is _______.
viii) Sodium Thiosulphate is used as an antacid. (True/False)
ix) Agents which act by precipitation of proteins in capillaries are known as:
a) Protectives
b) Astringents
c) Adsorbents
d) Cathartics.
x) Arsenic is used as a mineral supplement. (True/False)
xi) The solubility of iodine in water is increased by
a) Potassium Iodate
b) Potassium Iodide
c) Sodium Chloride
d) Ammonium Bromide.
xii) Barium Sulphate reagent as per I.P. contains Barium Chloride, Alcohol, water and _______.
xiii) The condition in which no hydrochloric acid is current in the stomach is known as
a) Hyperchlorhydria
b) Achlorhydria
c) Hypochlorhydria
d) Abschlorhydria.
xiv) Water for injection is free from
a) Bacteria
b) Bacteria and Pyrogens
c) Pyrogens
d) None of these.
xv) The most commonly used buffer in pharmacy is
a) Acetate buffer
b) Phosphate buffer
c) Sulphate buffer
d) Nitrate buffer.
xvi) Calamine contains Zinc Oxide and Ferric Oxide in the ratio of
a) 2 : 1
b) 98 : 2
c) 75 : 25
d) 90 : 10

Section-B

2) Attempt any 6 of the following: (4×6=24)
a) Describe the limit test of chloride as per I.P.
b) Describe the different kinds of glass used in pharmacy.
c) Discuss the different mechanisms by which antioxidants act.
d) Explain the apparatus and process of measurement of radioactivity.
e) Classify Antacids with examples and provide the method of preparation of Aluminium Hydroxide gel.
f) Describe the important compounds of iron used as hematinics.
g) Give the composition and uses of lactated Ringer Solution and Oral Rehydration Solution.
h) Classify the sources of impurities in pharmaceutical substances and discuss any 1 of them.

Section-C

Attempt any 4 of the following: (10×4=40)
3) Discuss the mechanism of action of anti-infective agents. provide the preparation and uses of Poirdone Iodine and Potassium Permanganate.
4) Give the methods of preparation and uses of (any four):
a) Calcium Levilinate
b) Magnesium Chloride
c) Titanium Dioxide
d) Sodium Fluoride
e) Nitrous Oxide.
5) Discuss coordination compounds and their applications in Pharmacy. provide the preparation of Calcium Folinate and Sodium Thiosulphate.
6) Explain the subsequent (any five):
a) Limit tests are semi-quantitative.
b) Radio-isotopes require special handling.
c) Maintaining acid-base balance in the body.
d) Cationic and anionic components of drugs used for systemic effects.
e) Oxygen for inhalation is used at a pressure greater than atmospheric pressure.
f) Limit tests in colored compounds.
7) Give the methods of preparation, identification tests and uses of (any four):
a) Sodium Hydroxide
b) Magnesium Trisilicate
c) Potassium Iodide
d) Aluminium Sulphate
e) Disodium Hydrogen Phosphate.

Earning:   Approval pending.