Uttar Pradesh Technical University (UPTU) 2009 B.Pharm Pharmaceutics-V (Pharmaceutical Technology-I) - Question Paper

Paper ID: 5034
B. Pharm (UPTU)
Fifth Semester Theory Examination, 2009-10
Pharmaceutics-V (Pharmaceutical Technology-I)

Time: three Hours Total Marks: 80

Note: 1) ans All ques..
2) All ques. carry equal marks.

1) Attempt any 2 parts of the following: (8×2)
a) How will you perform bulk characterization of a drug power, so as to be compressed into tablets?
b) Describe the solubility analysis of weakly acidic and weakly basic drugs. How can their bioavailability be enhanced?
c) How is stability of pharmaceutical products studied? How is it co-related to toxicology?

2) Attempt any 4 parts of the following: (4×4)
a) How do electrolytes act as flocculating agents?
b) What is low energy emulsification? elaborate its advantages?
c) When will you opt or prefer to prepare suspensions which are re-constituted before use, explain with examples? What kinds of suspending agents are used in preparation of suspensions to be re-constituted before use?
d) Discuss the valuation of suspensions.
e) How can physical stability of emulsions be enhanced?

3) Attempt any 2 parts of the following: (8×2)
a) Compare and contrast ranging from topical and transdermal preparations. How can penetration/absorption of drug be increased from ointments?
b) What is water number? explain in vitro and vivo valuation of ointments?
c) Discuss the manufacturing and formulation of sulphur ointment?

4) Attempt any 4 parts of the following: (4×4)
a) What are aquasols, explain their features and elaborate their advantages?
b) Classify different kinds of suppository bases, define with example.
c) What are the applications of aerosols?
d) Discuss the filling of aerosols in containers.
e) What are the valuation parameters of suppositories?

5) Attempt any 4 parts of the following: (4×4)
a) Discuss different kinds of emulsifying agents used in preparation of cold creams and vanishing creams. How are the creams prepared?
b) Discuss the formulating agents used in preparation of antidandruff shampoos.
c) What are the safe coloring agents used in preparation of lipsticks and nail lacquer? How are lipsticks prepared?
d) Compare and contrast antiperspirants and deodorants.
e) Give the properties and formulating agents of brushless shaving cream and after shave lotion.

Earning:   Approval pending.