Uttar Pradesh Technical University (UPTU) 2009 B.Pharm Pharmaceutical Analysis-III - Question Paper

B. Pharm (UPTU)
Seventh Semester Examination, 2009-10
Pharmaceutical Analysis-III

Time: three Hours Total Marks: 80

Note:
Attempt All ques..
All ques. carry equal marks.

1) Attempt any 4 of the following: (4×4=16)
a) Describe chromophores.
b) Explain deviations from Beer's legal regulations.
c) Describe a double beam UV spectrophotometer.
d) Discuss estimation by indirect method in colorimetry.
e) How does electronic excitation generate a spectrum?
2) Attempt any 4 of the following: (4×4=16)
a) Describe the sample handling in IR spectroscopy.
b) Write the qualitative and quantitative applications of IR spectroscopy
c) How is molecular structure related to fluorescence? provide examples.
d) What are the experimental factors which reason variation in fluorescence intensity?
e) How are IR spectra interpreted? discuss with examples.
3) Attempt any 2 of the following: (8×2=16)
a) Describe the origin of NMR spectra. elaborate NMR active compounds?
b) How and why do signals split in NMR spectroscopy? define 'delta' and 'tau' scales.
c) Explain the spectra of acetaldehyde, toluene and chloro-methanol.
4) Attempt any 2 of the following: (8×2=16)
a) Discuss the different rules of fragmentation.
b) Write the characteristics of a mass spectrum. elaborate molecular ion peak and pseudo-molecular ion peaks.
c) Explain the instrumentation of flame photometry. elaborate background emission and interference?
5) Attempt any 2 of the following: (8×2=16)
a) What are the flameless techniques used in Atomic Absorption Spectroscopy? provide the theory of Atomic Absorption.
b) Explain the theory and instrumentation of Emission photometry.
c) Discuss the pharmaceutical applications of Atomic Absorption Spectroscopy and emission photometry.

Earning:   Approval pending.