Baba Farid University of Health Sciences 2009 M.B.B.S [2nd Prof.] BF//11 Pharmacology - A - exam paper

M.M. : 40 Time : three Hours

Note : Attempt all ques..
USE SEPARATE ans SHEET FOR every PART.

PART - I

1. Enumerate the different routes of drug administration. Compare and contrast the advantages of Oral Vs. I.V. drug administration. [6]

2. Discuss the Pharmacological basis of the uses of:
a. Atropine in Preanesthetic medication. [2]
b. Neostigmine in Myesthenia gravis. [2]
c. Tamsulosin in Benign prostate hyperplasia. [2]
d. Ropinirole in Parkinsonism. [2]

3. Enumerate the different drugs used in the treatment of Epilepsy. explain the mechanism of actions, adverse effects of Phenytoin. [6]


PART – II

4. Discuss the Pharmacological basis of uses of the following:
a. Neostigmine in the reversal of Neuromuscular blockade by non-depolarising blockers. [2]
b. Nimodipine in Sub-arachnoid haemorrhage. [2]
c. Atropine in Organophosphate poisoning. [2]
d. GABA agonists/facilitators in Seizure control. [2]

5. Outline the Pharmacological basis of management of:
a. Status Asthmaticus. [3]
b. Anaphylactic shock. [3]

6. Write short notes on:
a. Non competitive drug receptor antagonism. [2]
b. Plasma protein binding of drugs. [2]
c. Receptor up and down regulation. [2]


-

Earning:   Approval pending.