Baba Farid University of Health Sciences 2010 M.D Bio-Chemistry [ BIOCHEMISTRY ] - Introductory Biochemistry & molecular Biochemistry [-I] - Question Paper

MD[ BIOCHEMISTRY ]

Introductory Biochemistry & molecular Biochemistry [Paper-I]

Time : three Hours M.M.: 100

Note: Attempt all ques..

1.What are the salient features of Genetic code? provide an account of different stages of translation of mRNA into protein and add a note on the inhibitors of this process. [6+8+6=20]


2.Describe the principles and methods involved in gene therapy and provide an account of major genetic disorders targeted for gene therapy. [10+10]


3. a. What is PCR? explain its applications. [10]
b. Discuss therapeutical applications of RNA interference . [10]


4. Write short notes on:
a. Collagen disorders. [7]
b. Protein misfolding. [7]
c. Inhibitors of Electron transport chain. [6]

5. Write short notes on:
a. Bohr effect. [5]
b. Oxidative DNA damage. [5]
c. Monogenetic diseases. [5]
d. Targeted genetic repair. [5]

Earning:   Approval pending.