Annamalai University 2007 M.Sc Bio Informatics MOLECULAR MODELING AND DRUG DESIGN - Question Paper

Register Number: 5920

Name of the Candidate:

M.Sc DEGREE EXAMINATION, 2007

(BIO-INFORMATICS)

(FOURTH SEMESTER)

(PAPER-XX)

420. MOLECULAR MODELING AND DRUG DESIGN

[Time : three Hours

Maximum : 100 Marks

ans any 5 ques.
All ques. carry equal marks

1. Discuss the physiochemical principles of drug action.

2. Write an account of lead discovery and optimization.

3. List out the current regulatory affairs on racemic drugs.

4. What are receptors? explain with suitable examples, the importance of receptors in drug design.

5. Write a detailed account on structure aided drug design.


6. Briefly define different in Silico methods used to model 3 dimensional structures.

7. Explain the various approaches adopted in drug design.

8. Discuss in detail about ADME and molecular descriptors.


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Earning:   Approval pending.