Annamalai University 2009-2nd Sem M.Sc Bio Informatics Biophysics (1st Semester ) - Question Paper

M.Sc. Bio Informatics 2009
1st Semester
Paper - III
Subject - Biophysics
Time - three hours
Maximum Marks - 100


ans Any 5 ques.. (5x20 = 100)


1. define the principle, instrumentation and kinds of mass spectrometer with a neat diagram.

2. How do you interpret the biological data using NMR? provide the principles of COSY and TOCSY.

3. discuss in detail the NMR imaging technique.

4. what are the principle and experimental aspects of UV-Vis spectroscopy. discuss how the protein concentration is determined.

5. discuss the method to determine the sedimentation coefficient of proteins and explain the various kinds of centrifugation involved in protein precipitation.

6. How the structure analysis is carried out using Raman Spectrometer? discuss.

7. define the principle of fiber diffraction. How is it applied to nucleic acids?

8. How do you interpret the electron density map in X-ray crystallography? discuss with an example.

Earning:   Approval pending.