Dibrugarh University 2012-3rd Year B.Sc Zoology B Sc - exam paper

2012
zoology (major) paper :30100
cell biology, genetics and genomics
[full marks:81]

part :A cell biology.[marks:41]
ans Q1 and any 3 from the rest

1. (a) select the accurate answer:[1*5]
i)The supporting framework of a cell consists of
1. microfilaments
2. microtubules
3. Both one and 2
4. none of the above

ii) Molecules of electron- transport chain of respiration are current in
1. mitochondrial matrix
2. intermembrane space
3. inner mitochondrial membrane
4. outer mitochondrial membrane

iii) Oxidation of glucose to CO2 and H2O occurs during
1. glycolysis
2. pentose-phosphate pathways
3. Krebs cycle
4. All of the above

iv) Which of the subsequent occupies the longest period in cell cycle?
1. Interphase
2. Prophase
3. Metaphase
4. Telophase

v) Histone proteins are synthesized in
1. M- phase
2. S-phase
3. G1- phase
4. g2-phase

(b) Distinguish ranging from any 3 of the following:[ 3*3 ]

i) Metaphase of mitosis and Metaphase of meiosis I
ii) Pinocytosis and Phagocytosis
iii) Microfilaments and Microtubules
iv) Prokaryotic genome and Eukaryotic genome

2. define the fluid- mosaic model of plasma membrane. explain about the function of plasma membrane.[6+3]

3. What is cell transformation? How does a neoplastic cell differ from its normal counterpart?3+6

4. Write short notes on the following:[3*3]
a) Giant chromosome
b) 3 dimensional structure of ribosome
c) G- protein

5. What do you mean by cell signalling? define the processes involved in edocrine signalling.2+7


part B:(Genetics and Genomics) [Marks:40]
ans Q6 and any 3 from the rest


6. (a) select the accurate answer:[1*4 ]

i) Mendelian recombination is due to
1. independent assortment of genes
2. linkage of genes
3. mutation
4. dominance

ii) Okazaki fragments are seen during
1. replication
2. transduction
3. transcription
4. translation

iii) Barr body in human female is formed by
1. inactivation of maternal X-chromosome
2. inactivation of paternal X chromosome
3. inactivation of either maternal or paternal X chromosome
4. inactivation of both maternal and paternal X chromosomes

iv) The clone of the sheep Dolly has been made by
1. gene transfer
2. nucleus transfer
3. somatic cell cloning

(b) Write short notes on any 3 [3*3]
i) Genomic library
ii) Southern blotting technique
iii) Super bug
iv) Human genome project

7. define the phenomenon of linkage. Why is linkage an exception to Mendels 2nd legal regulations of inheritance? [3+6]

8. Why the benefits o genetic engineering are real but hazards are hypothetical? discuss. [9]

9. discuss the following:[9]
a. XX-XY kind of sex determination.
b. Inborn errors in metabolism

10. What do you mean by cistron? Write the significance and practical implications of gene mutation.[2+7 ]

Earning:   Approval pending.