M.Sc-M.Sc BioTechnology 2nd Sem BT - 22 Genetics(University of Pune, Pune-2013)

                                   M.Sc. (Semester - II)

SEAT No. :

[Total No. of Pages : 1

BIOTECHNOLOGY

BT - 22 Genetics

(2005 Pattern)

Time : 1½ Hours]                                                                                         [Max. Marks :40

Instructions to the candidates :

1) Question No. 1 is compulsory. Out of remaining attempt 2 questions.

2) Neat diagrams must be drawn wherever necessary.

3) Figures to the right indicate full marks.

4) Your answers will be valued as a whole.

Q1) Write short notes on any four of the following

a) Law of Independent Assortment.

b) Hardy - Weinberg law

c) Polyploidy

d) Incomplete dominance

e) Prototrophs

[4 × 2.5 = 10]

Q2) a)      Explain the control of gene expression in bacteria with arabinose operon.[5]

b)       What is linkage? Explain how it can be used for gene mapping. [5] c)    Explain IS elements in bacteria.                                                                                                [5]

Q3) a)      Define gene interaction. Explain any one gene interaction with suitable

example.                                                                                                               [5]

b)       ‘Internal Environment plays an important role in the expression of genes’

Discuss with suitable examples.                                                                       [5]

c)       Define linkage and crossing over. Add a note on double crossovers. [5]

Q4) a)      Enlist chemical mutagens. Discuss the mechanism of action any typical

mutations caused by any one of them.                                                   [5]

b)       Define transformation. Explain the formation of competent cells and DNA

transfer by transformation.                                                                         [5]

c)       Explain importance of hybridisation in plant improvement.         [5]

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