M.Sc-M.Sc BioTechnology 1st Sem Cell Biology(University of Pune, Pune-2013)
M.Sc. (Semester - I) BIOTECHNOLOGY BT - 12 : Cell Biology
(Theory) (2005 Pattern)
SEAT No. :
[Total No. of Pages : 2
[Max. Marks : 80
Instructions to the candidates:
1) All questions are compulsory.
2) Figures to the right indicate full marks.
3) Draw neat labelled diagrams wherever necessary.
Q1) Answer in short :
a) Describe the term glyoxysome.
b) What is the endosymbiotic theory?
c) How do plasmodesmata help in the transfer of plant viruses? d) Define the term annulus.
e) Describe anterograde transport in brief.
f) What is the function of proteasomes?
g) Comment on the role of cellulose microfibrils in maintaining turgor
pressure of plant cells.
h) Differentiate between ER cisternae and ER lumen.
i) With suitable examples explain the term “transmembrane protein”.
j) Discuss the role of the contractile ring in cytokinesis briefly.
Q2) Attempt any two : [30]
a) Write short notes on :
i) Cyclic electron flow and its role in a plant cell.
ii) The role of different molecules in cell cycle arrest at the DNA damage
check points.
b) Answer the following :
i) What is treadmilling? Explain the role of GTP in microtubule
polymerization.
ii) What are the advantages of embryonic stem cells over adult stem
cells in therapeutic cloning?
c) Elucidate the role of the following :
i) Proplastids and Etioplasts in the development of chloroplasts. ii) APC in separation of sister chromatids.
P.T.O.
Q3) Attempt any three [30]
a) Explain the principle of confocal microscopy and add a note on its use
in Biology.
b) With the help of a diagram explain the death receptor pathway of
apoptosis.
c) How do cytoplasmic structures predict the plane of cell division before
mitosis begins in plant cells?
d) What are the characteristic features of nucleoporins that make up the
nuclear pore complex?
e) Describe the role of pRb as a tumor suppressor protein in regulating cell
cycle.
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| Earning: Approval pending. |
