M.Sc-M.Sc Bio Chemistry 1st Sem BCH - 170 : Biomolecules (University of Pune, Pune-2013)
M.Sc. (Semester - I)
BIOCHEMISTRY
SEAT No. :
[Total No. of Pages : 2
BCH - 170 : Biomolecules (2008 & 2010 Pattern)
Time : 3 Hours] [Max. Marks : 80
Instructions to the candidates :
1) All questions are compulsory.
2) Figures to the right indicate full marks.
3) Answers to the two sections should be written on separate answer books.
SECTION - I
Q1) Attempt any five of the following : [15]
How are macromolecules formed from their monomeric subunits? Give
examples.
List out the biological buffers and give their significance.
Write note on source, structure and biological functions of Ascorbic
acid.
Differentiate between anomers and epimers of glucose.
What are reducing and non-reducing sugars. Give examples.
Comment on amphipathic nature of phospholipids.
Q2) Attempt any three of the following : [15]
a) Give one example and structure of the following.
i) Phosphosphingolipid ii) Homodisacchoride
iii) Saturated fattyacid iv) Aminosugar
v) Ketohexose
b) What are fat soluble vitamins? Give their significance.
c) Elaborate on the major class and subclasses of lipids with examples.
d) Explain the reaction of glucose with phenyl hydrazine and Bromine water.
P.T.O.
Q3) Write notes on any two : [10]
a) Coenzymes.
b) Rancidity.
c) Mutarotation.
SECTION - II
Q4) Attempt any five of the following [15]
Explain the reactions of aminoacid with Ninhydrin and Sanger’s.
Differentiate betweena-helix and b-pleated sheet structures.
Comment on acid - base properties of aminoacid. List out various functions of proteins.
Write note on denaturation of proteins.
How are dipeptides formed? Give structure of Ala-Tyr.
Q5) Attempt any three of the following : [15]
a) Classify amino acids. Give two examples of each class.
b) Discuss the forces that stabilise tertiary structure of proteins.
c) Explain the titration curve of acidic amino acids.
d) How are ‘N’ an ‘C’ terminal aminoacids determined in a polypeptide?
Q6) Write notes on any two : [10]
a) Quaternary structure
b) Essential and Nonessential aminoacids.
c) Solid phase Synthesis.
| Earning: Approval pending. |
