M.B.B.S-M.B.B.S 2nd Year Pharmacology- Paper II(Kerala University of Health Sciences-2014)

Q.P. Code: 202001 Reg. no.: …………………
Second Professional MBBS Degree Examinations, March 2014
Pharmacology- Paper II

Time: 3 Hours                                                                            Total Marks: 50

• Answer all questions

• Draw diagrams wherever necessary

Essays: (2x6=12)

1. Enumerate the antibiotics which act by inhibiting cell wall synthesis. Mention the detailed
mechanism of action of any one of them on bacterial cell wall synthesis. Add a note on beta
lactamase inhibitors (2 + 2 +2 = 6)
2. Read the clinical problem and answer the following questions: 40 years old man who was on
metronidazole for amoebic dysentery went to a cocktail party where he consumed alcohol. After
some time, he started developing symptoms like flushing, burning sensation, throbbing headache,
dizziness, tightness in chest, vomiting.
• What is the reason for his symptoms.
• What are the other uses of metronidazole.
• What are the adverse effects produced by metronidazole (2 + 2 + 2 = 6)
Short notes: (5x3=15)
3. Alpha glucosidase inhibitors
4. Serious adverse effects produced by oral contraceptive pills
5. Azithromycin
6. Vinca alkaloids
7. Proton pump inhibitors
Answer briefly: (5x1=5)
8. Radical cure in plasmodium vivax infection
9. Drug used in thyrotoxic crisis
10. Super ORS
11. Adverse effects of metoclopramide
12. Antiseptics
Name two drugs: (8x1=8)
13. Topical anti fungals
14. Anti pseudomonal drugs
15. H2 blockers
16. Calcineurin inhibitors
17. Fluoroquinolones
18. Selective estrogen receptor modulators
19. First line anti tubercular drugs
20. Bisphosphonates
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